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Genomics week in brief: Week ending 20th November

Below, we have summarised some of the latest news and research from the genomics space from the past week.

Top stories from the past week

  • Researchers have identified a change in the tumour suppressor protein, PTEN, that extends healthy periods while maintaining longevity. (Park et al, 2021)
  • New research has suggested that the genes expressed in our brains may produce far more proteins than previously thought. (Leung et al, 2021)
  • By using multi-omic analysis, researchers have added evidence that altered fat metabolism plays a key role in amyotrophic lateral sclerosis. (Lee et al, 2021)
  • Researchers have provided new evidence on the safety of preimplantation genetic testing for aneuploidy. (Sanders et al, 2021)
  • Neurobiologists have identified a new gene important for healthy daily rhythms. (Lee et al, 2021)
  • A new study has found that an older-looking brain is linked to lower birth weight and genes. (Vidal-Pineiro et al, 2021)
  • Researchers have found new links between CRISPR gene-editing, p53 and other cancer genes. (Jiang et al, 2021)
  • New findings have revealed what genomic changes can happen in advanced cancer depending on the therapy received. (Zhang et al, 2021)
  • Scientists have discovered how the herpes virus kidnaps proteins to infect the nervous system for life. (Pegg et al, 2021)
  • Scripps Research scientists have mapped out how to block a brain-cell receptor which has been linked to depression and anxiety. (Patil et al, 2021)
  • Researchers have revealed a gene that suppresses the growth of colorectal cancer tumours. (Heino et al, 2021)
  • Novel gene therapy for haemophilia A has been shown to sustain expression of clotting factor and reduce bleeding events. (George et al, 2021)
  • Sloan Kettering Institute researchers have discovered a way in which genetic mutations occur during the formation of eggs and sperm. (Lukaszewicz et al, 2021)

In other news

  • The Translational Genomics Research Institute (TGen) will use a $500,000 grant from the Chan Zuckerberg Initiative (CZI) to expand the diversity of the Human Cell Atlas. (TGen, 2021)
  • Scientists have identified a second untreated HIV patient whose body shows no evidence of intact HIV genomes. (Turk et al, 2021)
  • Associate Professor Katherine Musliner from Aarhus University and Aarhus University Hospital Psychiatry has received funding to learn more about the genetics of borderline personality disorder. (Aarhus University, 2021)
  • The plans and goals for the Human Proteoform Project have been outlined. (Smith et al, 2021)
  • Experts have debated whether newborn babies should have their whole genomes sequenced. (Biesecker et al, 2021)

Image credit: canva