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Genomics week in brief: Week ending 20th May

Check out the latest Genomics Week in Brief – full of intriguing news and research from the genomics space!

Top stories from the past week

  • For the first time, researchers have described the mechanism of acquired resistance to DNA damage in a patient with small lung cancer. (Stanzione et al)
  • Using single-cell transcriptomics, scientists have illustrated how the inactivation of specific COMPASS and Polycomb complexes promotes the progression of pre-existing tumours. (Gaultier et al)
  • Researchers at the Broad Institute of MIT and Harvard have applied single-nucleus RNA sequencing to link specific cell populations to monogenic and polygenic diseases. (Eraslan et al)
  • Researchers designed self-uncloaking CRISPR-Cas13a-customized RNA nanococoons for spatial-controlled genome editing and precise cancer therapy. (Fan et al)
  • Researchers suggest a roadmap for building digital twins of the human immune system to further precision medicine approaches. (Laubenbacher et al)
  • A new report brings clearer perspectives on childhood Hodgkin Lymphoma, identifying potentially modifiable factors that might prevent or mitigate adverse outcomes. (Williams et al)
  • Researchers propose a new classification for hemochromatosis intended to avoid delays in diagnosis and treatment when detailed molecular characterisation is not readily available. (Girelli et al)
  • A team of researchers demonstrate a new paradigm for hematopoietic cell transplantation (HCT) donor selection that has an impact on the risk of relapse of malignant disorders. (Petersdorf et al)
  • South Korean researchers provide a multi-omics approach for understanding the immune system in miniature pigs to support pre-clinical trials. (Arora et al)
  • A recent study has shed light on how individual cell types communicate and interact to coordinate tissue regeneration. (Lucas et al)
  • Scientists used deep visual proteomics to define single-cell identity and heterogeneity. (Mund et al)
  • A community based cross-sectional study examined the cancers preventive practice and associated factors in North West Ethiopia. (Bantie et al)
  • Researchers in Spain have identified new targets to overcome HER2 blockades in breast cancer. (Adam-Artigues et al)

In other news:

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Cancer / Gene Editing / Genomics / Week in brief