Check out the latest Genomics Week in Brief – full of intriguing news and research from the genomics space!
Top stories from the past week
- For the first time, researchers have described the mechanism of acquired resistance to DNA damage in a patient with small lung cancer. (Stanzione et al)
- Using single-cell transcriptomics, scientists have illustrated how the inactivation of specific COMPASS and Polycomb complexes promotes the progression of pre-existing tumours. (Gaultier et al)
- Researchers at the Broad Institute of MIT and Harvard have applied single-nucleus RNA sequencing to link specific cell populations to monogenic and polygenic diseases. (Eraslan et al)
- Researchers designed self-uncloaking CRISPR-Cas13a-customized RNA nanococoons for spatial-controlled genome editing and precise cancer therapy. (Fan et al)
- Researchers suggest a roadmap for building digital twins of the human immune system to further precision medicine approaches. (Laubenbacher et al)
- A new report brings clearer perspectives on childhood Hodgkin Lymphoma, identifying potentially modifiable factors that might prevent or mitigate adverse outcomes. (Williams et al)
- Researchers propose a new classification for hemochromatosis intended to avoid delays in diagnosis and treatment when detailed molecular characterisation is not readily available. (Girelli et al)
- A team of researchers demonstrate a new paradigm for hematopoietic cell transplantation (HCT) donor selection that has an impact on the risk of relapse of malignant disorders. (Petersdorf et al)
- South Korean researchers provide a multi-omics approach for understanding the immune system in miniature pigs to support pre-clinical trials. (Arora et al)
- A recent study has shed light on how individual cell types communicate and interact to coordinate tissue regeneration. (Lucas et al)
- Scientists used deep visual proteomics to define single-cell identity and heterogeneity. (Mund et al)
- A community based cross-sectional study examined the cancers preventive practice and associated factors in North West Ethiopia. (Bantie et al)
- Researchers in Spain have identified new targets to overcome HER2 blockades in breast cancer. (Adam-Artigues et al)
In other news:
- What Genetics Can—and Cannot—Reveal about an Individual’s COVID Risk (Scientific American)
- People attribute prosocial behaviours to genetics more strongly than antisocial ones, study finds (PsyPost reports on Lebowtiz et al recent study.)
Image credit: canva
