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Genomics week in brief: Week ending 1st July

Check out the latest Genomics Week in Brief – full of intriguing news and research from the genomics space!

Top stories from the past week

  • A new study discovered that cancer cells depend on environmental lipids for proliferation. (Li et al)
  • An updated classification of myeloid neoplasms and acute leukaemia was established by international consensus and integrated morphological, clinical and genomic data. (Arber et al)
  • Research from the Institute of Cancer Research observed that GREM1 is required to maintain cellular heterogeneity in pancreatic cancer. (Lan et al)
  • A team from the University of North Florida identified a peptoid-based inhibitor that induces apoptosis and autophagy in cancer cells. (DuBose et al)
  • Researchers shed light on the interaction of background genetic risk, psychotropic medications and primary angle closure glaucoma in the UK Biobank. (Sekimitsu et al)
  • A new study suggested the absence of a region in transcription factor FOXP3 causes regulatory T cell instability in mice (Du et al)
  • Researchers conducted a meta analysis on the diagnostic accuracy of DNA-based SDC2 methylation test in colorectal cancer screening. (Wang et al)
  • A new deep learning technique revealed the exclusive functional contributions of individual cancer mutations. (Gupta et al)
  • Researchers from Kyushu University found a novel regulator that controls a multidrug resistance-associated protein in human renal cells. (Omata et al)
  • Scientists identified biomarkers that may predict the severity of multiple sclerosis. (Petržalka et al)
  • Whole genome CRISPR sequencing discovered a genetic and therapeutic vulnerability in calreticulin mutations in myeloproliferative neoplasms. (Jutzi et al)
  • A team presented genotype imputation and polygenic score estimation in a north-western Russian population, a previously understudied group. (Kolosov et al)
  • Scientists have discovered antibody signatures that correlate with less severe cases of dengue in children. (Diasjr et al)
  • A new study demonstrated how mitochondrial RNA modifications shape metabolic plasticity in metastasis. (Delaunay et al)
  • Researchers observed that mutations linked to neurological disease enhance the self-association of low-complexity protein sequences. (Zhou et al)

In other news:

  • Can rubrics combat gender bias in faculty hiring? (Science)
  • Technology feature: How to make spatial maps of gene activity down to the cellular level. (Nature)
  • A new report uncovers large number of previously uncounted rare diseases. (RareX)
  • Unleashing the power of big data to guide precision medicine in China. (Nature)
  • Abortion bans will impact doctors’ treatment of cancer. (Bloomberg)
  • Ancient DNA reveals five streams of migration into Micronesia and matrilocality in early Pacific seafarers. (Science)
  • Cancer risks cascade through generations for some families. But there are high hopes for precision medicine. (ABC News)
  • New molecular target could result in cancer drugs with fewer side effects. (SciTechDaily based on Journal of Cell Science)
  • New gene editing tool reduces errors by nicking DNA not cutting. (NewAtlas based on Science Advances)
  • Octopus and human brains share the same “jumping genes”. (Interesting Engineering based on BMC Biology)  
  • Blockchain not just for bitcoin: It can secure and store genomes, too. (Yale School of Medicine)
  • Researchers pioneer a new way to detect microbial contamination in cell cultures. (MIT News)

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Cancer / Gene Editing / Genomics / Week in brief