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Genomics week in brief: Week ending 1st July

Check out the latest Genomics Week In Brief – full of intriguing news and research from the genomics space!

Top stories from the past week:

  • A large genome-wide association study has revealed the first genetic variants linked to faster disease progression in MS patients (Nature).
  • A team of Japanese researchers have developed a new type of alpha particle therapy that could treat many types of cancer (Chemical Science).
  • A new DNA barcoding technique can identify specific types of plant waste in human faeces. The tool has the potential to revolutionise attempts to monitor and improve human nutrition (PNAS).
  • A study has shown the mechanisms behind cell fate conversion, a process often implicated in cancer (eLife).
  • Scientists have identified a long-non-coding RNA that plays a significant role in cancer invasion (PNAS).
  • A gene found in human airway cells blocks the replication of bird flu particles (Nature).
  • A large-scale study of human cancers has shed light on how chromosomal changes influence tumour cells (Nature).
  • Researchers have used base editing to restore fetal haemoglobin expression in the cells of patients with sickle cell disease (Nature Genetics).
  • Mice with a genetic form of deafness have normal neural activity in the ear up until the usual onset of hearing at around 2 weeks old, according to a recent study (PLOS Biology).
  • Researchers have discovered a programmable eukaryotic RNA-guided system that could be used in gene editing (Nature).
  • Scientists have analysed how DNA moves, shedding light on the dynamics of gene expression (Science).
  • An analysis of the first ever genetically modified pig heart to be transplanted into a human has been published. It details the reasons that led to the heart’s eventual failure two months after the procedure (The Lancet).

In other news:

  • A UK university has joined a collaborative to transform dementia care. The University of Edinburgh forms part of the NEURii collaboration which aims to use data and machine learning to create digital treatment solutions (University of Edinburgh).
  • A large study has suggested that vitamin D supplements could lower the risk of cardiovascular disease (BMJ).
  • The NHS have announced a pilot scheme that will see all smokers and previous smokers in England offered lung cancer screening in middle age (The Guardian).