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Genomics week in brief: Week ending 18th December

Your final Genomics Week in Brief of the year – filled with the latest genomics news and research from the past week.

Top stories from the past week

  • Mount Sinai researchers have solved a major mystery in cancer research – how cancer cells remain dormant for years before metastasis occurs. (Martino et al, 2021)
  • Scientists have discovered how the absence of a genetic switch can lead to malformations during embryonic development. (Rouco et al, 2021)
  • A team of researchers has discovered a novel gene, Ciliated Left-Right Organzser Metallopeptidase (CIROP), that governs left-right asymmetry within the human body. (Szenker-Ravi et al, 2021)
  • A study of an investigational gene therapy has found that a single dose can reverse sickle cell disease for at least three years in some patients. (Kanter et al, 2021)
  • Researchers have developed a new tool, called Giraffe, that can efficiently map new genome sequences to a pangenome representing many diverse human genome sequences. (Siren et al, 2021)
  • New research has found that adding mRNA can improve the response to cancer immunotherapy in patients who previously weren’t responding to the treatment. (Wen et al, 2021)
  • A new paper has described a breakthrough using CRISPR-Cas9 to target fat cells that could help in the study of obesity. (Romanelli et al, 2021)
  • Researchers have found that a gene that aids cancer proliferation may also be a potential new target for deadly pulmonary hypertension. (Baker, 2021)
  • Australian researchers have uncovered more than 1,300 genes linked to congenital heart disease. (Nim et al, 2021)

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Cancer / CRISPR / Genomics / Week in brief