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Genomics week in brief: Week ending 16th January

Your latest genomics week in brief – jam-packed with the latest genomics news and research!

Top stories from the past week

  • Scientists have developed a new humanised mouse model that allows them to examine resistance to immune checkpoint blockade therapies in melanoma. (Herlyn et al, 2021)
  • Researchers have identified a gene involved in the growth of breast cancer, which may lead to potential new targets for treatment. (Wang et al, 2021)
  • Researchers have put forward a safe and efficient new stem cell therapy for regenerating cardiac function in paediatric patients with a rare heart condition. (Hirai et al, 2021)
  • A new study has provided new details on how the MLL4 gene causes Kabuki syndrome, a rare developmental disorder. (Lee et al, 2021)
  • New research suggests that mutations within tandem repeat regions may play a significant role in autism spectrum disorders. (Gymrek et al, 2021)
  • Researchers have developed a new technique to analyse environmental DNA from water samples. Using this technique, the team uncovered genes of invasive fish. (Andres et al, 2021)
  • In a new study, researchers used CRISPR/Cas9 genome editing to achieve a tenfold increase in the production of ‘super-bug’ targeting formicamycin antibiotics. (Hutchings et al, 2021)
  • New insights reveal that recurring glioblastoma tumours with very few mutations are far more vulnerable to immunotherapies than similar tumours with an abundance of mutations. (Ashley et al, 2021)
  • Cancer research has shown how mutations in RUNX1 can cause different types of disease. (Bonifer et al, 2021)
  • Using data from RNA-folding experiments, researchers have generated the first-ever data-driven movies of how RNA folds as it is made by cellular machinery. (Lucks et al, 2021)

Events

  • Join us next week for our annual Festival of Genomics & Biodata. The Festival is the UK’s largest Genomics event. This year we’re expecting over 5,000 attendees from across the globe. It is taking place between 26-29th January – so register now.
  • Join us for our brand-new three-part webinar series – ‘Multi-Omics ONLINE’ . We will be bringing together global experts who are harnessing diverse datasets to advance our understanding of human health and disease. Register now.

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Genomics / Immunotherapy / Week in brief