In the latest genomics week in brief, we have summarised all of the most recent and exciting genomics news and research.
Top stories from the past week
- Researchers have developed a machine-learning technique that can identify epigenetic drivers of various cancers. (Pan et al, 2021)
- New research has found that many oesophageal cancers can turn on ancient viral DNA that was embedded in our genome hundreds of millions of years ago. (Wu et al, 2021)
- Researchers have developed a spatial atlas of early-stage lung cancer and surrounding normal tissue at single-cell resolution, providing a key resource for studying tumour development and identifying novel therapeutic targets. (Sinjab et al, 2021)
- A new study has shed light on the genetic prehistory of populations in modern Italy through the analysis of ancient individuals from the Bronze Age transition. (Saupe et al, 2021)
- Gladstone researchers have fine-tuned CRISPR-Cas9 genome editing to work on human immune cells called monocytes. (Hiatt et al, 2021)
- Scientists have developed a novel genetic sensor – CopyCatcher – which harnesses CRISPR-based gene drive technology to detect when a genetic element has been copied precisely from one chromosome to another throughout cells in the body. (Li et al, 2021)
- Using metagenomic sequencing, researchers have identified changes in the gut microbiome that occur after spinal cord injury. (Du et al, 2021)
- New findings have revealed epigenetic changes that are unique to B cells and B cell subtypes that subsequently drive their fate. (Mahajan et al, 2021)
In other news
- Pfizer has enrolled the first UK participant into the global Phase 3 investigational gene therapy study for Duchenne Muscular Dystrophy. (Duchenne UK, 2021)
- Join us for the next webinar in our series – ‘Genomics in Drug Discovery & Development’. In this webinar, we explore the different technologies biopharma is leveraging for functional genomics studies. It is taking place on Thursday 20th May at 3pm BST/4pm CEST/10am EST. Register here to watch the webinar live or on-demand.
- Join us on Tuesday 25th May at 3pm BST/4pm CEST/10am EST for a one-off webinar – ‘Single Cell Sequencing: A New Dimension in Cancer Diagnosis and Treatment’. This webinar will provide a case study on single-cell profiling of tumour heterogeneity. It will also outline the new single-cell technologies that were used for this study. Register here to watch the webinar live or on-demand.
- Check out our latest report – ‘Multi-omics: An integrative approach to biomedical research’. This report explores the motivations behind embarking on multi-omics studies, highlights some of the recent success stories, and discusses methods for approaching analysis. You can download the guide for free here.