Check out the latest Genomics Week in Brief – full of intriguing news and research from the genomics space!
Top stories from the past week
- A new deep learning method revealed treatment targets in dilated cardiomyopathy, a genetic heart condition with no cure. (Yang et al)
- A new study explained how individual cells process large amounts of information. (Kramer et al)
- Researchers identified the shared gene signatures and pathways between polycystic ovary syndrome and endometrial cancer using an omics based combined approach. (Miao et al)
- New research has pinpointed persister cells that survive chemotherapy. (Rehman et al)
- Researchers from the University of Oxford presented the value of UK Biobank for endocrine and metabolic disorders. (Bešević et al)
- A new metanalysis and review found genetic polymorphisms associated with susceptibility to COVID-19 disease and severity. (Dieter et al)
- Researchers found that early immunotherapy treatment can rev up anti-tumour cells. (Nature)
- Researchers from ETH Zurich found that combining single-cell tracing and omics improved blood stem cell fate regulator identification. (Wehling et al)
- A new study found that genome-wide DNA hypermethylation opposes healing in chronic wound patients. (Singh et al)
- New research has identified α-CD38 antibodies as valuable in treating B cell malignancies. (Camponeschi et al)
- Researchers have generated custom pooled CRISPR libraries for genetic dissection of biological pathways. (Gulbranson et al)
- Researchers created an off-the-shelf, single-dose solution for achieving prolonged systemic serum levels of protein immunotherapeutics via adeno-associated virus gene transfer. (Cripe et al)
- A new study used CRISPR to reveal genes implicated in COPD in type 2 alveolar epithelial cells. (Werder et al)
- New research determined that PPP2R2D suppressed effector t cell exhaustion and inhibited tumour growth in melanoma. (Pan et al)
- Japanese researchers identified three themes for the information needs of children with leukaemia and outlined beneficial communication approaches. (Yamaji et al)
In other news:
- Limiting the environmental impact of pharmaceuticals. (Science)
- A treaty to break the pandemic cycle. (Science)
- Physicians spreading misinformation on social media – do right and wrong answers still exist in medicine? (New England Journal of Medicine)
- Cell map of human gonads identifies the cells involved in sex determination. (Wellcome Sanger Institute)
- A patient has undergone gene-editing to lower their cholesterol. (MIT Technology Review)
- Scientists zero in on genetic causes of Parkinson’s disease. (Yale News)
- A 57-year-old man received a heart transplant from a genetically modified porcine animal. (New England Journal of Medicine)
- First genetic map of one of humans oldest parasites. (Wellcome Sanger Institute)
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