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Genomics week in brief: Week ending 15th January

Below, we have summarised some of the latest news and research across the genomics space – enjoy!

Top stories from the past week

  • A world-first study has shown that space travel can lower red blood cell count, known as space anaemia. (Trudel et al, 2022)
  • Scientists have discovered new links between the breakdown in brain cell development and risk of schizophrenia. (Sanders et al, 2022)
  • A new study has found that boosting one gene in cells that assist the brain’s neurons can slow Alzheimer’s progression in mice. (Jiwaji et al, 2022)
  • A team of researchers has provided insight into why severe depression affects women and men differently. (Dion-Albert et al, 2022)
  • A recent study has provided evidence supporting the involvement of MAPK4 in triple-negative breast cancer. (Wang et al, 2022)
  • Preliminary findings from an ongoing first-in-human trial with CAR macrophages has shown the cell therapy may be safe and feasible for solid tumours. (Penn Medicine, 2022)
  • A new study has uncovered the genetic pathways underlying obesity that could help develop more personalised strategies to maintain healthy weight. (Hysi et al, 2022)
  • NIH researchers have developed the first stem cell model of albinism to study related eye conditions. (George et al, 2022)
  • A study has revealed important insights into the molecular mechanisms that underpin the body’s defences against the development of skin cancer. (Avolio et al, 2022)
  • A team of computer scientists has created a cloud-based platform that grants genomics researchers easy access to one of the world’s largest genomics databases. (Schatz et al, 2022)
  • By studying genes which are altered in people with lymphoma, researchers have identified a key mechanism involved in disease development. (Schick et al, 2022)

In other news

  • A medical team at University of Maryland Medical Center has transplanted the first genetically engineered pig heart into a 57-year-old man. (Kotz, 2022)
  • Ten hospitals in the Sanford Children’s Genomic Medicine Consortium are participating in whole genome sequencing research of patients with suspected inborn errors of immunity. (Sanford Health, 2022)

Image credit: canva


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