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Genomics week in brief: Week ending 13th March

Another jam-packed week of interesting research and news from the genomics space – all summarised here for you!

Top stories from the past week

  • Researchers have found a key mechanism that allows deadly bacteria to gain resistance to antibiotics. (Feng et al, 2021)
  • Scientists have identified the basic mechanisms that regulate HIV expression, which can provide insight into HIV replication, latency and pathogenesis. (Pedro et al, 2021)
  • Using PRS analysis software, researchers have shown that combining information on an individual’s genetic risk of heart attack with their LDL level can help determine those most at risk from heart attack. (Bottà et al, 2021)
  • When PMP22 is made twice as much as normal, type 1A of genetic Charcot-Marie Tooth disease develops. French scientists have now developed a patented therapy based on reducing RNA coding for the PMP22 protein. (Massaad-Massade et al, 2021)
  • New results show, for the first time, that telomeres respond to external signals that induce cell proliferation. In addition, blocking these signals can interfere with cancer cells becoming immortal. (Blasco et al, 2021)
  • New research suggests that microbes in the gut may contribute to certain symptoms associated with complex neurological disorders. (Costa-Mattioli et al, 2021)
  • Using a nanopore, researchers have demonstrated the potential to reduce the time required for sequencing a glycosaminoglycan from years to minutes. (Xia et al, 2021)
  • Scientists have developed a technique which works by analysing compounds found in sebum and identifying changes in people with Parkinson’s Disease. (Barran et al, 2021)
  • Children’s Hospital of Philadelphia have identified genes responsible for hematopoietic stem cell regeneration via the assembly of the ribosome. (Tong et al, 2021)
  • New study provides a detailed view of how hepatitis B virus establishes chronic infection. (Wei and Ploss, 2021)
  • Researchers have discovered a protein – Prosaposin – that appears to play an important role in atherosclerosis. (Van Leent et al, 2021)
  • For the first time ever, a research team has peered inside a human cell to view a multi-subunit machine responsible for regulating gene expression. (Abdella et al, 2021)

In other news

  • The second person ever to naturally cure their HIV has been identified in Argentina. (The Times, 2021)

Events

  • Join us for the next webinar in our brand-new series – ‘Next-Gen PCR ONLINE’. In this series, we highlight how next-gen PCR methods can impact modern science. The next webinar is taking place on Thursday 18th March at 3PM GMT/4PM CET/10AM EST. Register now.

Reports

  • Download our latest report: ‘Liquid Biopsy: Current Status and Future Directions’. This report will provide you with an overview of liquid biopsy technologies, exclusive interviews with key leaders in the field and insights into the current technical and social barriers impacting clinical uptake. Get your free copy here.
  • In its third edition, ‘The Sequencing Buyer’s Guide’ is the go-to-guide for helping people in the genomics space understand the sequencing landscape, save time and money, and make better purchasing decisions. Download your free copy of the guide here.

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