It’s getting cold outside, but we have plenty of genomics news to help you fight the winter blues! Check out the latest Week in Brief below.
New diagnostic methods have been in the spotlight…
An AI-powered blood test has been developed to detect the earliest signs of breast cancer. The screening method combines a laser analysis technique with machine learning, and could lead to earlier intervention and improved prognosis (Journal of Biophotonics).
A new AI tool has been developed that can analyse placentas shortly after birth, providing faster and more accurate insights into infant and maternal health. By examining a photograph of the placenta, the technology can identify abnormalities associated with infection (Patterns).
A blood test that detects and analyses small fragments of circulating tumour DNA could be used to determine prognosis for patients with prostate cancer. This could help to inform treatment decisions (Nature Communications).
Cancer research has made headlines…
A new chemotherapy regimen for Hodgkin lymphoma shows fewer severe side effects while maintaining effectiveness, according to a recent study. The treatment reduces risks such as infertility, offering a safer option for patients (The Lancet Oncology).
Researchers have developed a gene therapy method that utilises light-activated electrical currents to induce cell death in aggressive tumours (Cancer Research).
A study has revealed that a patient’s microbiome can influence their response to immunotherapy against recurrent ovarian cancer. This finding could improve outcomes for those suffering from this condition, which is currently incurable (Nature Communications).
Researchers have made progress understanding evolution and the influence of our genes…
Scientists from several institutions across the UK and abroad are joining forces to understand how whole genome duplication gives rise to complex traits and new gene functions. The process has shaped many species, and is crucial to our understanding of evolution (Sanger Institute).
Scientists have uncovered a key genetic mechanism that influences the development of facial structures in humans. This research sheds light on how specific genetic changes shape distinct facial features, offering insights into certain congenital disorders (AJHG).
A recently published review has assessed over 100 genetic studies related to human reproductive traits. This comprehensive overview shows how our genes influence everything from the age we have children, to the onset of the menopause and aging-related health outcomes (Nature Aging).
What else has gone on this week?
Researchers have created “mini-brains” in the lab to study how mitochondrial dysfunction contributes to brain diseases like epilepsy. This new model, created using advanced stem cell technology, could lead to better treatments for these conditions (Advanced Science).
The impact of your diet could persist through multiple generations, according to a new study. In an experiment conducted in mice, a low protein diet was seen to lead to lower birthweights and smaller kidneys as far as four generations down the line (Heliyon).
Check out last week’s Week in Brief here.
