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Genomics week in brief: Week ending 12th February

Check out the latest Genomics Week in Brief – full of intriguing news and research from the genomics space!

Top stories from the past week

  • A team of researchers has reprogrammed the tumour microenvironment of liver cancer by using mRNA nanoparticles. (Xiao et al, 2022)
  • Scientists have shown that it is possible to modify the mitochondrial genome in live mice which could pave the way for new treatments for mitochondrial disorders. (Silva-Pinheiro et al, 2022)
  • By using an optogenetic approach, researchers were able to inhibit parathyroid hormone secretions to prevent bone loss in culture and animal models. (Liu et al, 2022)
  • Tel Aviv University researchers have engineered functional human spinal cord tissue and restored walking abilities when implanted into lab models. (Wertheim et al, 2022)
  • A recent study has discovered that KRAS mutations cause rearrangements of chromatin inside cells. (Murthy et al, 2022)
  • Bioengineers have created a new RNA editing technology that makes it simpler to repair disease-causing mutations without compromising precision or efficiency. (Katrekar et al, 2022)
  • A team of researchers has applied cutting-edge DNA sequencing approaches to characterise over 20,000 variants in 273 genes of medical importance. They used these results to formulate benchmarks that will help others sequence these genes more accurately. (Wagner et al, 2022)
  • Researchers have made new advances in connecting the evolution of pregnancy and cancer metastasis. (Suhail et al, 2022)
  • New findings have suggested that more widespread use of genetically modified crops could have a positive effect on the climate. (Kovak et al, 2022)
  • By mapping mutation hotspots in cancer, researchers have uncovered new drivers and biomarkers. (Bergstrom et al, 2022)
  • Researchers have developed the largest catalogue of gene activators. (Alerasool et al, 2022)
  • By studying the SAP97 protein, researchers have identified a specific location in the brain where schizophrenia may originate. (Kay et al, 2022)
  • New research has reported that deactivation of the gene PLa2g7 partially mimics the anti-aging effects of caloric restriction in mice. (Spadaro et al, 2022)
  • According to a recent study, the brain’s ability to clear a protein linked to Alzheimer’s is controlled by the circadian cycle. (Clark et al, 2022)

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Cancer / Gene Editing / Genomics / Week in brief