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Genomics week in brief: Week ending 11th September

Check out our latest Genomics Week in Brief – a summary of some of the latest genomics news and research.

Top stories from the past week

  • Researchers have built a detailed cellular map of chronic multiple sclerosis lesions, identifying key genes that play a role in lesion repair. (Absinta et al, 2021)
  • An international team has compared genomic changes in cancer cells that are eradicated by and resistant to treatment, identifying potential molecular targets for prostate cancer therapy. (Ketola et al, 2021)
  • Using CRISPR-based genetic engineering, researchers have created a system that restrains populations of mosquitoes. (Li et al, 2021)
  • Researchers have developed a new addition to the CRISPR toolbox – Cas7-11 – which is able to target RNAs without the collateral effects seen in other systems. (Özcan et al, 2021)
  • According to a recent study, there is no evidence to suggest that stem cell transplants lead to changes in DNA. However, researchers did find that anti-viral drugs may cause DNA changes. (Kanter et al, 2021)
  • New findings suggest that genetic or drug-induced manipulations of the complement pathway could improve the outcomes of mild and severe traumatic brain injury. (Holden et al, 2021)
  • Researchers have developed a single-cell and spatially resolved transcriptomic map of human breast cancers. (Wu et al, 2021)
  • A CRISPR-Cas9 origin study has uncovered a class of transposon-encoded RNA-guided nucleases, dubbed “OMEGA”, that could be harnessed for genome editing in human cells. (Altae-Tran et al, 2021)

In other news

  • The Hastings Center has announced the launch of a new open-access resource that aims to counter misinformation on genomic studies of human behaviour. (Martschenko et al, 2021)
  • Washington University School of Medicine in St. Louis has received a $7 million grant from the NIH to help lead national efforts to explore how variations in the human genome sequence affect how the genome functions. (WashU, 2021)
  • Several Nobel Prize winners have written a collection of scientific articles that are now available for young people. The Nobel Collection, published by Frontiers, aims to improve young people’s access to learning material. (Frontiers for Young Minds, 2021)

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