The adoption of single cell analysis approaches is accelerating, leading to rapid progress in our understanding of complex biological systems. However, severe limitations in single cell approaches remain, requiring the rapid development of new approaches and technologies.
Using two ground-breaking case studies presented by eminent researchers in their field, this webinar will outline several brand-new innovative approaches in single cell analysis that will remove some of these limitations – including the capturing and preservation of the widest range of cells (including those that are sensitive to degradation), and the use of time-resolved transcriptomics.
Following a short introduction, the first webinar talk – delivered by Professor Hao Chen of the Medical School of Nantong University – will present a comprehensive spatio-temporal atlas of mouse epididymal cells using innovative single-cell RNAseq methods. This will include a novel method to detect time-resolved RNA dynamics, using case studies from both recently published work (see the reference below) and unpublished work.
The second webinar talk – delivered by Dr. Julie Laliberte, Head of R&D at Singleron Biotechnologies – will outline a new, cutting edge (yet simple) approach to ensure that you truly ‘leave no cell behind’, capturing the most cell types, including those that are prone to degradation, as well as reduce bias for species and cell types.
What you will learn from this webinar:
- Leave no cell behind: How to overcome the limitations of sample multiplexing, to remove species and cell-type bias, using a completely, antibody-independent new method based on “click chemistry”. This ground-breaking method will ensure that you capture the most cells types, including those that are prone to degradation.
- Take your single cell analysis from ‘photo’ to ‘video’: Move beyond a taking a ‘snapshot’ to obtain time-resolved transcription dynamics, allowing you to observe ‘new’ versus ‘old transcripts across time. This will be illustrated using a specific case study from a mouse model used to study reproductive system development.
Talk 1: Spatio-temporal landscape of mouse epididymal cells defined by large-scale single-cell RNA-seq
Speaker: Prof Hao Chen, Institute of Reproductive Medicine, Medical School of Nantong University
Talk 2: Leave no cell behind: Cutting-edge chemical engineering for innovative single cell applications
Speaker: Dr. Julie Laliberte, Head of R&D, Singleron Biotechnologies
Followed by Q&A with all speakers
Register for Webinar