Since its inception, CRISPR has made signification strides towards personalised medicine. It currently offers options for tailored treatment based on an individual’s genetic profiling, for novel drug target identification/validation and for precise therapeutic interventions. However, major challenges remain in tool development and tool optimisation.
The 2024 iteration of the CRISPR & Gene Editing Webinar Series will present the latest advances in overcoming these challenges, leaving you with key insights from the latest adoptions of CRISPR in drug discovery and patient treatment.
Register to the Advances in CRISPR & Gene Editing Webinar
**Please note that by registering for the first webinar in the series you will automatically gain access to the subsequent webinars in the series**
By attending this webinar series, you will:
- Get an overview of the CRISPR tools and technologies available, alongside their shortcomings
- Learn about the advancements in gene editing technology for higher accuracy and better safety profiles
- Discover the potential of CRISPR-based gene therapy to allow early detection of haematological malignancies
Who will you hear from?
- Rina Kansal, Academic Haematopathologist, University at Buffalo; Associate Medical Director, Versiti Blood Center of Wisconsin
- Gabriele Casirati, Senior Research Fellow, DFCI, Harvard Medical School
- Antonio Garcia Guerra, Senior Post-Doctoral Researcher, Department of Paediatrics, University of Oxford
- Manoj Kandpal, Director, Rockefeller University
- Mandana Arbab, Lodish Family Assistant Professor of Neurology, Boston Children’s Hospital & Harvard Medical School
Mark your calendar for 14th & 21st November 2024 at 3pm BST / 4pm CET / 10am EST
Webinar 1: Gene Editing in Early Development – Target Identification & Validation
Thursday, 14th November 2024 at 3pm BST / 4pm CET / 10am EST
Recent advances have seen CRISPR utilised to explore new targets for a wide range of disorders beyond cancers and rare diseases. Yet, the true potential of CRISPR has yet to be realised for drug discovery.
This webinar will discuss how gene editing tools and technology can aid drug developers in their efforts to improve drug target identification and validation. Our three speakers will each highlight unique applications of CRISPR in early drug development.
Talk 1: Computational Methods for Genome Editing: Design, Quantification, and Risk Assessment
- Luca Pinello, Associate Professor, Massachusetts General Hospital & Harvard Medical School
Talk 2: Developing Therapeutic CRISPR Genome Editing for Spinal Muscular Atrophy
- Mandana Arbab, Lodish Family Assistant Professor of Neurology, Boston Children’s Hospital & Harvard Medical School
Webinar 2: Improvements in CRISPR Technology for Safer and More Accurate Targeting
Thursday 21st November 2024 at 3pm BST / 4pm CET / 10am EST
CRISPR is a powerful tool, used to edit genetic material to treat genetic disorders with unprecedented precision. However, it’s safety and accuracy are still a concern.
Join Webinar 2 of this series to discover the latest advancements in CRISPR gene editing technology through four unique clinical case studies highlights the benefits of it. Find out how CRISPR can improve treatments, with higher accuracy and reduced off-target effects, for more promising patient outcomes.
Talk 1: General Overview of CRISPR Analysis Pipeline & Key Points to Consider
- Manoj Kandpal, Director, Rockefeller University
Talk 2: Pre-Analytical Pitfalls and the Power of Standards: Why ISO for Liquid Biopsies Matters
- Antonio Garcia Guerra, Senior Post-Doctoral Researcher, Department of Paediatrics, University of Oxford
Talk 3: Conceptualising CRISPR-based Gene Therapy for Personalised Treatment of Haematological Malignancies with Underlying Germline Predispositions
- Rina Kansal, Academic Haematopathologist, University at Buffalo; Associate Medical Director, Versiti Blood Center of Wisconsin
Talk 4: Epitope Base Editing to Achieve Immune-Based Selection of Multiplex Genome Engineered Cells
- Gabriele Casirati, Senior Research Fellow, DFCI, Harvard Medical School
