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LSD1 promotes prostate cancer cell reprogramming through TP53 repression

Prostate cancers are generally treatable with positive survival outcomes. However, following common treatments such as androgen receptor inhibitors, some prostate […]

p53 controls cell metabolism to prevent genomic instability

p53 has long been called the “guardian of the genome,” but how is this tumour suppressor protein maintaining genomic stability […]

Spinning a Yarn with the p53 Cancer Protein

Written by Charlotte Harrison, science writer  The tumour suppressor protein p53 is a key controller of cell proliferation. Mutations that […]

Targeting p53 for Successful Tumour Suppression

Exposure to radiation can wreak havoc on cells, tissue and organs. However, some tissues are more vulnerable to radiation damage […]

Compound in green tea may increase levels of p53

A new study, published in Nature Communications, has provided insights into the mechanisms of a compound in green tea and […]

Genomics Week in Brief: Week Ending 17th May

We know there’s never a quiet week in the genomics world, that’s why in Week in Brief we’ve sourced the […]

Key cross-species genes offer insight into human bladder cancer development

Muscle invasive bladder cancer (MIBC) is an aggressive form of human bladder cancer. Little is currently known about the genetic […]

Gene expression differences drive motor neuron lineage decisions

The pathways driving neuronal development and function are generally well characterized. However, how the diversity of neuronal subtypes is established […]

Five New Genes Linked to Breast Cancer 

An international collaborative research paper published last week in Nature Genetics has identified several new genes associated with breast cancer […]

UK’s Higher Skin Cancer Rates Defy UV Index

A recent collaboration between the Wellcome Sanger Institute and the Skin Research Institute of Singapore (SRIS) has been published in […]