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Evaluation of ctDNA assays for precision oncology

An international team has reported findings from an independent assessment of five commercially available ctDNA assays as a method to […]

Beyond companion diagnostics – what next for ctDNA liquid biopsy in the NHS?

Liquid biopsy has the promise to revolutionise cancer care and treatment, allowing the detection of rare cell types with a […]

ctDNA informs treatment in BRAF-mutated melanoma

Researchers find that cell-free circulating tumour DNA (ctDNA) analyses before and during treatment could help guide selection of therapy for […]

NSCLC: Implementing ctDNA analysis in the clinic

A recent review, published in Cancers, has summarised the current landscape of ctDNA analysis in clinical practice as well as […]

ctDNA and metabolites in CSF serve as novel biomarkers for CNS germ cell tumours

Researchers have validated the use of circulating tumour DNA (ctDNA) and metabolites in cerebrospinal fluid (CSF) as potential biomarkers for […]

An overview of alternative fluids in liquid biopsy

The “liquid” in liquid biopsy most commonly refers to blood. However, the human body contains many other fluids and biological […]

An overview of alternative biomarkers in liquid biopsy

The most common analytes in liquid biopsies are CTCs and ctDNA. However, there is so much more that can be […]

The application of liquid biopsy in cancer

Liquid biopsy has seen a lot of development and many applications in the field of cancer diagnostics. Key applications include […]

The history and development of liquid biopsy

Obtaining an effective diagnosis is the crucial first step in the treatment of cancer and many other diseases. Unfortunately, invasive […]

A guide to liquid biopsy and non-invasive diagnosis

Liquid biopsy offers an innovative solution for the diagnosis and monitoring of cancer and other diseases. However, traditional invasive biopsy […]