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Evaluation of ctDNA assays for precision oncology

An international team has reported findings from an independent assessment of five commercially available ctDNA assays as a method to […]

Beyond companion diagnostics – what next for ctDNA liquid biopsy in the NHS?

Liquid biopsy has the promise to revolutionise cancer care and treatment, allowing the detection of rare cell types with a […]

ctDNA informs treatment in BRAF-mutated melanoma

Researchers find that cell-free circulating tumour DNA (ctDNA) analyses before and during treatment could help guide selection of therapy for […]

NSCLC: Implementing ctDNA analysis in the clinic

A recent review, published in Cancers, has summarised the current landscape of ctDNA analysis in clinical practice as well as […]

ctDNA and metabolites in CSF serve as novel biomarkers for CNS germ cell tumours

Researchers have validated the use of circulating tumour DNA (ctDNA) and metabolites in cerebrospinal fluid (CSF) as potential biomarkers for […]

Next-Generation PCR ONLINE

The advent of PCR methods has enabled the detection and quantification of nucleic acids in small sample sizes. Just recently, […]

Nanopore sequencing combined with liquid biopsy analysis

A recent study, published in Clinical Chemistry, has presented a rapid nanopore genotyping strategy to enable amplification-free identification and classification […]

The value of microsatellite instability testing – now and in the future

Microsatellite instability (MSI) testing of tumour tissue is routinely performed to identify genomic instability (deficiency in one or more DNA […]

Potential drug targets for paediatric germ cell tumours

Researchers have performed a comprehensive genetic analysis and identified potential drug targets for paediatric germ cell tumours (GCTs). Germ cell […]

Liquid Biopsy ONLINE – A Virtual series

As we continue to improve our understanding of cancer biology, one thing remains a game-changer for cancer care: the ability […]