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Methods to study cell-cell communication from single-cell sequencing data

This feature on cell-cell communication is adapted from part of Chapter 4 of the 2023 Spatial and Single-cell Playbook. Organisms […]

LSD1 promotes prostate cancer cell reprogramming through TP53 repression

Prostate cancers are generally treatable with positive survival outcomes. However, following common treatments such as androgen receptor inhibitors, some prostate […]

A new role for RNA editing in immune-cell trafficking

Written by Charlotte Harrison, Science Writer A paper published in the journal Immunity has identified a new role for the […]

To Bleb or Not to Bleb: Researchers Unravel How Cancer Cells Evade Anoikis

In a recent paper, published in Nature, researchers have discovered that blebbing might be a survival strategy in melanoma cells, […]

Single-Cell and Spatial Data Reveals How Hodgkin Lymphoma Cells Evade Immune Attack

In a new study, published in the journal Blood, researchers from the Wellcome Sanger Institute have used single-cell and spatial […]

Researchers use single-cell and spatial-omics to create a detailed atlas of human lung development

In a recent paper published in Cell, researchers at the Wellcome Sanger Institute, EMBL’s European Bioinformatics Institute, the Gurdon Institute […]

How skin cells-turned-neurons are shedding light on Huntington’s disease

Researchers at Washington University School of Medicine have discovered the mechanism driving cognitive decline in Huntington’s disease patients. The study, […]

Largest scRNA spatial atlas of B cells in lung cancer revealed

Written by Lauren Robertson, Science Writer. Researchers from the University of Texas MD Anderson Cancer Center have revealed the largest […]

Lactate found to regulate T cell anti-tumour activity

Written by Lauren Robertson, Science Writer As our understanding of the role of metabolites in the body increases, and as […]

Large-scale CRISPR screens show RASA2 ablation boosts the efficacy of T cell therapies

Written by Miyako Rogers, Science Writer In a new study published in Nature, researchers used CRISPR screens to identify the […]