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Back to Basics – Base & Prime Editing

In our most recent Back to Basics feature, we took a look at CRISPR, the gene editing technique that took […]

Base and Prime Genome Editing in Precision Oncology

This feature on prime and base editing is adapted from content provided in the Cancer Genomics 2023 Report. The introduction […]

Cell-based study corrects fragile X syndrome

Written by Charlotte Harrison, Science Writer. A new paper published in Cell describes an approach to correct the genetic defect […]

Base editing successfully corrects immune deficiency mutation

Researchers have used base editing to correct the mutation that causes a rare immune disorder. A one-off gene therapy could […]

Uncovering Novel MAPK Interactors: A Novel Yeast-based Genetic Screening Platform

In a recent study published in Science, researchers have developed a yeast-based genetic screening pipeline for evaluating large numbers of […]

CRISPR-based therapy alleviates Huntington’s disease symptoms in mouse models

Researchers have investigated the application of RNA-targeting CRISPR technology in the treatment of Huntington’s disease (HD). The study, published in […]

Novel nanoparticle-based chemoimmunotherapy shrinks tumours in mice

Researchers have developed a nanoparticle-based approach to overcome the immunosuppressive microenvironment of tumours. The study, published in Nature Nanotechnology, detailed […]

Researchers develop an mRNA-based vaccine for rabies

Researchers at Liverna Therapeutics have developed a new vaccine candidate for the deadly rabies virus using mRNA-based technology. With no […]

Exploring RNA in saliva-based liquid biopsies: A new frontier in precision diagnostics

Detecting early signs of disease is often crucial to achieving the best possible patient outcomes. To date, blood-based liquid biopsies have […]

Treating inherited deafness with RNA base editing

Using RNA base editing techniques, scientists have successfully reversed a genetic form of hearing loss in a mouse model. The […]