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Genome-wide CRISPR and tumour suppressor genes could open new pathways for discovering anticancer drugs

Researchers at the University of Texas have performed genome-wide CRISPR screens to uncover vulnerabilities critical for discovering anticancer drugs. The […]

Transcriptional-translational conflict prevents tumour progression in bladder cancer

The process of transcriptional-translational conflict has been defined in a recent paper, published in Cancer Cell. This represents a new […]

Targeting p53 for Successful Tumour Suppression

Exposure to radiation can wreak havoc on cells, tissue and organs. However, some tissues are more vulnerable to radiation damage […]

Evolutionary arms race: artificial selection for host resistance to tumour growth

Researchers have used artificial selection to observe the evolutionary arms race between tumour cells and the host immune response. Evolutionary […]

Five New Genes Linked to Breast Cancer 

An international collaborative research paper published last week in Nature Genetics has identified several new genes associated with breast cancer […]

LSD1 promotes prostate cancer cell reprogramming through TP53 repression

Prostate cancers are generally treatable with positive survival outcomes. However, following common treatments such as androgen receptor inhibitors, some prostate […]

Genomics week in brief: Week ending 8th April

Check out the latest Genomics Week in Brief – full of intriguing news and research from the genomics space! Top […]

An overview of cancer biology

Original post by Liam Little in February 2023. Updated by Ashleigh Davey in September 2023. Cancer is a disease of […]

A guide to cancer genomics

Original post by Liam Little in February 2023. Updated by Ashleigh Davey in September 2023. According to the British Journal […]

Researchers Investigate the Epigenetic Regulation of NRG1 in Breast Cancer Under Hyperglycaemia

In a new study published in Nature, researchers investigated the molecular mechanisms behind the epigenetic regulation of the NRG1 enhancer […]