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TISCH: a tumour microenvironment single-cell transcriptomic database

Researchers at Tongji University, Shanghai, have developed a large-scale curated database that integrates tumour microenvironment (TME) single-cell transcriptomic data, known […]

Insight into the distinct tumour immune microenvironments in gastric cancer patients

Researchers have compared the tumour immune microenvironments (TIMEs) of primary gastric cancers and found distinct patterns between primary and metastatic […]

Premalignant tumours composition and cell changes defined with single-cell analyses

A new study identified key changes in gene expression and tissue composition in premalignant tumours, providing potential targets for prevention, […]

Arming CAR-T cells to fight solid tumours

Written by Charlotte Harrison, Science Writer  Immunotherapy with chimeric antigen receptor T cells (CAR-T cells) has yielded impressive anticancer responses […]

How do tumour cells use collagen to become dormant?

Researchers have discovered that collagen is key for the ability of tumour cells to enter a dormant life cycle, with […]

CAR T-cells activated by heat destroy solid tumours

Despite its success against liquid tumours, CAR T-cell therapy often has no impact on solid tumours. A new study, published […]

Blood stem cells are linked to the progression of aggressive brain tumours

Using transcriptome analysis and gene expression sequencing, researchers have discovered that blood stem cells (HSPCs) cause increased cell division in […]

New Biomarkers of Childhood Brain Tumours Identified in Cerebrospinal Fluid

Paediatric brain tumours are the leading cause of tumour-related mortality in children. There is a widespread search for predictive biomarkers […]

Mathematical model predicts tumour evolution

Researchers from Barts Cancer Institute and The Institute of Cancer Research (ICR) London have developed a computational model that maps […]

Colorectal Cancer Genomic Differences in Patients with African and European Ancestry

Colorectal Cancer Genomic Differences in Patients with African and European Ancestry  Written by Vered Smith, Science Writer  Scientists have published […]