Researchers at Tongji University, Shanghai, have developed a large-scale curated database that integrates tumour microenvironment (TME) single-cell transcriptomic data, known […]
Researchers have compared the tumour immune microenvironments (TIMEs) of primary gastric cancers and found distinct patterns between primary and metastatic […]
Researchers have developed a nanoparticle-based approach to overcome the immunosuppressive microenvironment of tumours. The study, published in Nature Nanotechnology, detailed […]
Written by Lauren Robertson, Science Writer As our understanding of the role of metabolites in the body increases, and as […]
A new study identified key changes in gene expression and tissue composition in premalignant tumours, providing potential targets for prevention, […]
Written by Charlotte Harrison, Science Writer Immunotherapy with chimeric antigen receptor T cells (CAR-T cells) has yielded impressive anticancer responses […]
Researchers have discovered that collagen is key for the ability of tumour cells to enter a dormant life cycle, with […]
Despite its success against liquid tumours, CAR T-cell therapy often has no impact on solid tumours. A new study, published […]
Using transcriptome analysis and gene expression sequencing, researchers have discovered that blood stem cells (HSPCs) cause increased cell division in […]
Paediatric brain tumours are the leading cause of tumour-related mortality in children. There is a widespread search for predictive biomarkers […]
