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Resolving the driving forces behind tumour heterogeneity

Researchers have recently developed an in vitro model that can distinguish between the genetic, epigenetic and stochastic factors underlying tumour […]

Intra-tumour heterogeneity across human cancer genomes

As part of the Pan-Cancer Analysis of Whole Genomes Consortium, researchers analysed the whole genomes of tumour samples from over […]

Resolving tissue heterogeneity in bone, kidney and liver cancer using in situ spatial transcriptomics

The winners of the 2021 Spatial Biology EACR & NanoString Grant program, in collaboration with Illumina, will present cancer research […]

Pan-cancer tumour organoids pave the way towards precision medicine

Researchers have developed a platform of pan-cancer tumour organoids and a neural-network-based drug assay, that has the potential to advance […]

Machine learning and Darwin combined to piece together tumour genetics

MOBSTER – model-based clustering in cancer, is a machine learning tool that incorporates theoretical population genetics from Darwin to examine […]

TISCH: a tumour microenvironment single-cell transcriptomic database

Researchers at Tongji University, Shanghai, have developed a large-scale curated database that integrates tumour microenvironment (TME) single-cell transcriptomic data, known […]

Clinical and Genomic Profiles of Black Patients with Prostate Cancer

Written by Sharmin Begum, science writer  Black patients who were diagnosed with metastatic hormone-sensitive prostate cancer (mHSPC), have been analysed […]

Genomic Sequencing Offers Young Cancer Patients New Treatment Options

Written by Charlotte Harrison, Science Writer  The results from a clinical trial that sequenced DNA and RNA in tumours from […]

Applying RNA-sequencing Technology to Cancer and Rare Diseases

Written by Vered Smith, Science Writer  A paper in Molecular Biology Reports has recently reviewed the latest RNA sequencing technologies, […]

Single-Cell Analysis of Gastric Cancer Provides New Disease Insights

Written by Charlotte Harrison, Science Writer  The tumour heterogeneity of gastric cancer, and its metastasis to different organs, makes effective […]