Researchers have performed a comprehensive genetic analysis and identified potential drug targets for paediatric germ cell tumours (GCTs). Germ cell […]
Researchers have used artificial selection to observe the evolutionary arms race between tumour cells and the host immune response. Evolutionary […]
Researchers from Barts Cancer Institute and The Institute of Cancer Research (ICR) London have developed a computational model that maps […]
MOBSTER – model-based clustering in cancer, is a machine learning tool that incorporates theoretical population genetics from Darwin to examine […]
Researchers have compared the tumour immune microenvironments (TIMEs) of primary gastric cancers and found distinct patterns between primary and metastatic […]
Researchers have validated the use of circulating tumour DNA (ctDNA) and metabolites in cerebrospinal fluid (CSF) as potential biomarkers for […]
Researchers at Tongji University, Shanghai, have developed a large-scale curated database that integrates tumour microenvironment (TME) single-cell transcriptomic data, known […]
The immune system is constantly on the lookout for threats, but cancer isn’t always easy to spot. Some cancer cells […]
Luca Magnani from Imperial College London spoke at the Festival of Genomics 2020.
Tumours often avoid detection by CD8+ T cells through disrupting peptide presentation by major histocompatibility complex class I (MHC-I). However, […]
