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Transcriptome and circular DNA sequencing in single cancer cells

A new single-cell sequencing method has been published in Nature Genetics. Single-cell extrachromosomal circular DNA and transcriptome sequencing (scEC&T-seq) can […]

Multimodal tissue characterisation with spatial protein and transcriptome sequencing

A new study, published in Nature Biotechnology, presents Spatial PrOtein and Transcriptome Sequencing (SPOTS) for high throughput combined spatial transcriptomics […]

Epitranscriptome biomarkers successfully distinguish early and late-stage prostate cancer

Written by Lauren Robertson, Science Writer As one of the leading causes of cancer-related deaths for men in the US […]

TWAS: Transcriptome-wide association study

A recent trend in large-scale association studies is transcriptome-wide association study (TWAS), which aggregates genomic information into functionally relevant units […]

A Guide to Multi-omics Integration Strategies

This feature was put together with content from Chapter 2 of the upcoming multi-omics playbook, due to be released on […]

Spatial transcriptomics and multiomics in cancer research

Spatial context matters in complex biology. From cancer prevention to cancer biology, and for both translational and clinical studies, multiomic spatial […]

The State Of: Genomics in Aging

Aging is a natural and inevitable part of life, but the way we age and the traits we typically associate […]

Exemplar uses of multi-omics in drug discovery

The drug discovery process can be long and gruelling, but when backed by genetic evidence, drugs are twice as likely […]

The Spatial and Single-Cell Analysis Playbook

Spatial and single-cell omics is one of the fastest developing areas in genomics, and keeping up is a challenge. How […]