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Transcriptome and circular DNA sequencing in single cancer cells

A new single-cell sequencing method has been published in Nature Genetics. Single-cell extrachromosomal circular DNA and transcriptome sequencing (scEC&T-seq) can […]

Multimodal tissue characterisation with spatial protein and transcriptome sequencing

A new study, published in Nature Biotechnology, presents Spatial PrOtein and Transcriptome Sequencing (SPOTS) for high throughput combined spatial transcriptomics […]

Epitranscriptome biomarkers successfully distinguish early and late-stage prostate cancer

Written by Lauren Robertson, Science Writer As one of the leading causes of cancer-related deaths for men in the US […]

TWAS: Transcriptome-wide association study

A recent trend in large-scale association studies is transcriptome-wide association study (TWAS), which aggregates genomic information into functionally relevant units […]

A link between schizophrenia and the placenta

Written by Charlotte Harrison, Science Writer. The genetic risk of schizophrenia is believed to be linked largely to genetic variants […]

A new role for RNA editing in immune-cell trafficking

Written by Charlotte Harrison, Science Writer A paper published in the journal Immunity has identified a new role for the […]

ARRDC5: a newly identified regulator of spermatogenesis

Written by Charlotte Harrison, Science Writer A study by researchers at Washington State University indicates that a molecule called ARRDC5 […]

Human gene expression varies across days and seasons

In a recent study, published in the journal PLOS Biology, researchers have investigated the variation of human gene expression over […]

Single-Cell and Spatial Data Reveals How Hodgkin Lymphoma Cells Evade Immune Attack

In a new study, published in the journal Blood, researchers from the Wellcome Sanger Institute have used single-cell and spatial […]