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Macrophage-targeted CAR T cells offer new hope for cancer therapy

Researchers at the Icahn School of Medicine (Mount Sinai, New York) have found that macrophage-targeted CAR T cells are capable […]

Lactate found to regulate T cell anti-tumour activity

Written by Lauren Robertson, Science Writer As our understanding of the role of metabolites in the body increases, and as […]

Large-scale CRISPR screens show RASA2 ablation boosts the efficacy of T cell therapies

Written by Miyako Rogers, Science Writer In a new study published in Nature, researchers used CRISPR screens to identify the […]

CRISPR screen unveils the stickiness of T cells

A new study has pinpointed a previously unknown molecular inhibitor of T cell adhesion. The study, published in Science Signalling, […]

New microfluid device for T cell selection aids precision cancer immunotherapy

A newly invented microfluid device can isolate potent T cells for cancer immunotherapy.   A new study, published in Advanced Healthcare […]

IL-33 secreting senescent cells offer new target for obesity-based liver cancer

New research has discovered how senescent cells and their secretion of IL-33 can encourage immunosuppression and tumour expansion in obesity-linked […]

T cell activation experiment boosts search for immune disease treatments

In a first-of-its-kind experiment, researchers have identified links between 127 genes and immune diseases. The study provides new insights into […]

Arming CAR-T cells to fight solid tumours

Written by Charlotte Harrison, Science Writer  Immunotherapy with chimeric antigen receptor T cells (CAR-T cells) has yielded impressive anticancer responses […]

Sequencing of adult cells provides insight into human embryogenesis

How the human embryo develops is a complex and unclear phenomenon. Scientists are faced with many challenges when it comes […]

Targeting T cells against brain cancer

Researchers have reprogrammed regulatory T cells in the brain to fight against the most aggressive type of brain cancer – […]