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PRMT5: synthetic lethality target in pancreatic cancer cells

A team of researchers have used targeted CRISPR screening and have identified PRMT5 as a synthetic lethality combinatorial target with […]

Genome-wide CRISPR and tumour suppressor genes could open new pathways for discovering anticancer drugs

Researchers at the University of Texas have performed genome-wide CRISPR screens to uncover vulnerabilities critical for discovering anticancer drugs. The […]

The diversity of cancer targets

Here we summarise a recent paper, published in Cell, that explored the landscape of therapeutic cancer targets beyond the list […]

Reversing pancreatic cancer progression

Scientists have engineered human pancreatic cancer cells (Panc-1) to reprogram and revert them back to their normal state following PTF1A […]