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Genetic atlases reveal new landscapes in brain structure

An international team has used genetic atlases of the human brain to identify hundreds of new genomic loci that help […]

The impact of protein structure prediction on variant interpretation

A new review paper, published in the Journal of Molecular Biology, has investigated the impact of advanced protein structure prediction […]

AlphaFold 2 open up protein structure prediction software for all

Source code for AlphaFold 2, an algorithm that predicts 3D protein structure with unprecedented accuracy, is now freely available. Proteins […]

The functional importance of unusual DNA structures called G4s has been revealed

For the first time, researchers have found that G-quadruplex structures (G4s) in DNA could be added to the list of […]

White matter microstructure in the brain is influenced by genetic variants

Recently, a genome-wide association study has identified genetic variants that influence white matter microstructure in the brain. White matter was […]

The effects of DNA methylation on 3D structure

Researchers have explored how methylation patterns have a protein-independent regulatory role that increases the stiffness of DNA, which ultimately impacts […]

The 3D genome structure impacts fertility

A study led by scientists at the Universitat Autònoma de Barcelona (UAB) has demonstrated that alterations in the 3D organisation […]

Cancer cells take advantage of DNA’s 3D structure

Researchers have explored how cancer cells re-organise the 3D structure of their DNA to enhance oncogene activity. Cancer cells In […]

First early human embryo structure

University of Exeter researchers have discovered a simple and efficient approach to recreate the early structures of the human embryo […]

Structures of the heart reveal risk to cardiovascular disease

A recent study published in Nature has explored the fractal structure of the heart, revealing its influence on susceptibility to […]