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Single-cell analysis reveals lung cancer therapy transcriptional changes

A study reported in Cell has shown through single-cell analysis that targeted lung cancer therapies result in transcriptional changes that […]

The human endometrium at a single-cell level

Researchers have characterised the transcriptomic transformation of the human endometrium during the menstrual cycle at single-cell resolution.  Human endometrium During […]

TISCH: a tumour microenvironment single-cell transcriptomic database

Researchers at Tongji University, Shanghai, have developed a large-scale curated database that integrates tumour microenvironment (TME) single-cell transcriptomic data, known […]

scREAD: single-cell RNA-Seq database for Alzheimer’s Disease

Researchers at The Ohio State University have developed an integrated database known as scREAD – single-cell RNA-Seq database for Alzheimer’s […]

Biologically-validated AI is how scientists are realising the full potential of single-cell RNA sequencing

The promise of single-cell gene expression data Genomic data are an excellent source of novel disease biomarkers and targets. In […]

Single-cell copy number profiling unveils the genetic diversity of cancer

The genetic information of a cancerous tumour is typically obtained by sequencing the tumour cells together, rather than analysing them […]

Eleven challenges in single-cell data science

Introduction: Single-cell sequencing technology has been advanced by the falling sequencing costs, a boom in microfluidics and combinatorial indexing strategies. […]

Study finds chemokine receptor inhibition can overcome immune hyperactivation in COVID-19 patients

A new single-cell analysis study of airway samples of COVID-19 patients has found that drugs targeting chemokine receptors may be […]

Gut microbiota predicts Crohn’s disease state

Researchers have revealed the potential usage of cytometric fingerprints of gut microbiota as a diagnostic tool to predict Crohn’s disease […]