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Single-cell analysis reveals lung cancer therapy transcriptional changes

A study reported in Cell has shown through single-cell analysis that targeted lung cancer therapies result in transcriptional changes that […]

Single cell analysis provides insight into primary resistance

Using single cell analysis, researchers have revealed cell populations that can predict primary resistance to imatinib in chronic myeloid leukaemia. […]

Biology at High Resolution – Advances in Single Cell Analysis: A Review

After being voted Nature’s ‘Method of the Year’ in 2013 and 2019, it is not surprising that researchers are increasingly […]

The human endometrium at a single-cell level

Researchers have characterised the transcriptomic transformation of the human endometrium during the menstrual cycle at single-cell resolution.  Human endometrium During […]

TISCH: a tumour microenvironment single-cell transcriptomic database

Researchers at Tongji University, Shanghai, have developed a large-scale curated database that integrates tumour microenvironment (TME) single-cell transcriptomic data, known […]

scREAD: single-cell RNA-Seq database for Alzheimer’s Disease

Researchers at The Ohio State University have developed an integrated database known as scREAD – single-cell RNA-Seq database for Alzheimer’s […]

Biologically-validated AI is how scientists are realising the full potential of single-cell RNA sequencing

The promise of single-cell gene expression data Genomic data are an excellent source of novel disease biomarkers and targets. In […]

Single-cell copy number profiling unveils the genetic diversity of cancer

The genetic information of a cancerous tumour is typically obtained by sequencing the tumour cells together, rather than analysing them […]

Eleven challenges in single-cell data science

Introduction: Single-cell sequencing technology has been advanced by the falling sequencing costs, a boom in microfluidics and combinatorial indexing strategies. […]