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A guide to single-cell sequencing and spatial analysis

Introduction The human body contains over 35 trillion cells, with tissues and organs comprising of many different cell types constantly […]

An overview of single-cell RNA sequencing and spatial transcriptomics

Single-cell RNA sequencing (scRNA-seq) has become the most established and widely used technique within single-cell analysis. Spatial transcriptomics is quickly […]

RNA-sequencing of amniotic fluid cells for prenatal diagnosis of rare disorders

A team of researchers from Hong Kong have developed a proof-of-concept RNA-sequencing approach to analyse amniotic fluid to diagnose rare […]

Single nucleus RNA sequencing reveals potential treatment for Huntington’s disease

In a recent paper, published in Nature Communications, a team of scientists used single nucleus RNA sequencing (snRNAseq) to investigate […]

Multimodal tissue characterisation with spatial protein and transcriptome sequencing

A new study, published in Nature Biotechnology, presents Spatial PrOtein and Transcriptome Sequencing (SPOTS) for high throughput combined spatial transcriptomics […]

Healthy newborns offered whole genome sequencing to screen treatable rare genetic disorders

Genomics England have partnered with the NHS  to implement the Newborn Genomes Programme. Whole genome sequencing (WGS) will be used […]

Advances in Genomic Sequencing ONLINE

The sequencing landscape is changing more rapidly than ever before: The cost of sequencing is decreasing (welcome to the $100 […]

Bringing choice to sequencing – DNBSEQ technology and the HotMPS sequencing chemistry*

Next Generation Sequencing (NGS) has become a powerful tool to decipher the genetic code. It is often seen as having […]

Exome sequencing study identifies new genes and variants involved in Crohn’s disease

Written by Miyako Rogers, Science Writer A new study published in Nature uses large-scale exome sequencing to identify new genes […]

Exploring rare cancer mutational signatures with whole genome sequencing

Written by Liam Little, Science Writer A new study, published in Science, has used whole genome sequencing (WGS) to explore […]