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Genetic signature of treatment resistance in breast cancer identified

Researchers have discovered a genetic signature that can identify drivers of poor outcomes in advanced oestrogen-receptor positive (ER+) breast cancer. […]

Antimicrobial resistance: This is not just a phage

I worked at a pharmacy for over seven years. During that time, thousands of prescriptions for antibiotics came and went. […]

Vulnerable genes may combat antibiotic resistance

Target-based antibiotics act on the products of essential genes but rarely result in bacterial death. A new study published in […]

Predictability of resistance to anticancer drugs

Researchers have explored the predictability of genetic versus nongenetic resistance mechanisms to anticancer drugs in melanoma. Development of resistance Metastasis […]

Understanding the role of genetic resistance in the UK ash tree population

This article was compiled from a recent webinar, delivered by Professor Richard Buggs and supported by Novogene, a genomic services […]

The origins of antibiotic resistance

By comparing thousands of bacterial genomes, researchers have traced back the evolutionary history of antibiotic resistance genes. Antibiotic resistance Antibiotic […]

Single cell analysis provides insight into primary resistance

Using single cell analysis, researchers have revealed cell populations that can predict primary resistance to imatinib in chronic myeloid leukaemia. […]

Non-Genetic Mechanisms of Therapeutic Resistance in Cancer

Therapeutic resistance has repeatedly proved itself to be an unconquerable barrier for curative cancer treatment. However, recent investigations have challenged […]

Evolutionary arms race: artificial selection for host resistance to tumour growth

Researchers have used artificial selection to observe the evolutionary arms race between tumour cells and the host immune response. Evolutionary […]

Heterochromatin-dependent processes contribute to fungal resistance

Researchers from the University of Edinburgh have identified how fungal resistance to drugs develops. Originally, researchers thought that only mutations […]