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Single cell analysis provides insight into primary resistance

Using single cell analysis, researchers have revealed cell populations that can predict primary resistance to imatinib in chronic myeloid leukaemia. […]

Non-Genetic Mechanisms of Therapeutic Resistance in Cancer

Therapeutic resistance has repeatedly proved itself to be an unconquerable barrier for curative cancer treatment. However, recent investigations have challenged […]

Evolutionary arms race: artificial selection for host resistance to tumour growth

Researchers have used artificial selection to observe the evolutionary arms race between tumour cells and the host immune response. Evolutionary […]

Heterochromatin-dependent processes contribute to fungal resistance

Researchers from the University of Edinburgh have identified how fungal resistance to drugs develops. Originally, researchers thought that only mutations […]

Genetically engineered probiotics

Advancements in the field of synthetic biology, genetic engineering and genome sequencing technologies have provided the opportunity to improve the […]

The Association for Molecular Pathology Annual Meeting

We attended this year’s annual meeting of The Association for Molecular Pathology. It was a virtual meeting that took place […]

CRISPR system destroys cancer cells

Researchers have utilised lipid nanoparticles to deliver CRISPR technology and found that this technology could destroy cancer cells within an […]

Lung microbiome implicated in lung cancer pathogenesis and prognosis

A recent paper, published in Cancer Discovery, has found that enrichment of the lungs with oral commensal microbes was associated […]

Mutation-induced remodelling in Pseudomonas aeruginosa

Clinical isolates of Pseudomonas aeruginosa from patients with cystic fibrosis have revealed mutation-induced remodelling of the BfmRS two-component system. Thereby, […]

NSCLC: Implementing ctDNA analysis in the clinic

A recent review, published in Cancers, has summarised the current landscape of ctDNA analysis in clinical practice as well as […]