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An RNA-targeting drug alleviates ALS and dementia

Researchers at the University of Florida Scripps Biomedical Research centre have developed a drug capable of penetrating the blood-brain barrier […]

TIGER: a tool to predict CRISPR–Cas13 off-target activity

‘TIGER: a tool to predict CRISPR–Cas13 off-target activity‘ – Written by Charlotte Harrison, Science Writer. CRISPR technology that targets RNA […]

CRISPR-based therapy alleviates Huntington’s disease symptoms in mouse models

Researchers have investigated the application of RNA-targeting CRISPR technology in the treatment of Huntington’s disease (HD). The study, published in […]

Treating inherited deafness with RNA base editing

Using RNA base editing techniques, scientists have successfully reversed a genetic form of hearing loss in a mouse model. The […]

Modified guide RNAs boost CRISPR-Cas13 transcript knockdown

Researchers at New York University and the New York Genome Center have developed chemically modified guide RNAs that enhance CRISPR-Cas13 […]

Round-up: COVID-19 October 2020 (Part One)

President Donald Trump caught “a blessing from God” (COVID-19) and the UK is on the verge of another national lockdown […]