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RNA modifications provide new insights into disease brain states

Recently, researchers have used advanced microscopy to investigate the role that RNA modifications play in ‘synaptic tagging’ within the brain. […]

Exploring Alzheimer’s disease using single-cell/nucleus RNA sequencing data

Scientists have developed a network-based methodology that leverages single-cell/nucleus RNA sequencing data to uncover novel therapeutic targets for Alzheimer’s disease. […]

Discovering the importance of placental microRNAs

Researchers have carried out the most comprehensive profiling of human placental miRNA expression to date, in the hope of driving […]

New CRISPR-Cas System is Found to Cut RNA

Researchers at the Delft University of Technology have discovered a new CRISPR-Cas system that is able to cut viral RNA […]

Modified guide RNAs boost CRISPR-Cas13 transcript knockdown

Researchers at New York University and the New York Genome Center have developed chemically modified guide RNAs that enhance CRISPR-Cas13 […]

RNA-binding protein deletion leads to leukaemia disease attenuation

New research led by scientists from UCLA has shown that the deletion of an RNA-binding protein can significantly increase survival […]

Reversing diabetes with a selective microRNA inhibitor

Researchers have designed a structure-specific microRNA inhibitor that selectively represses a microRNA family member, which may in turn reverse the […]

How to do RNA sequencing

RNA sequencing is an NGS technique that enables investigation of the transcriptome – the total cellular content of RNAs, including […]

RNA modifications can protect against non-alcoholic fatty liver disease

Researchers have revealed that post-transcriptional RNA modifications protect against the development of non-alcoholic fatty liver disease. This mechanism may also […]

The role of microRNAs in broken heart syndrome

Scientists from Imperial College London have identified the role of two key microRNAs in the development of broken heart syndrome. […]