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Search results for: Polygenic risk score

Moving Polygenic Risk Scores into the Clinic

Genetic testing is widely used to diagnose monogenic diseases that are caused by mutations in a single gene, such as […]

Sepsis-Associated Variants Integrated into Polygenic Risk Score

Written by Vered Smith, Science Writer  Researchers at the University of Michigan have published a study in PLOS ONE identifying […]

Schizophrenia polygenic risk scores: The struggle of improving their clinical utility

Researchers have analysed clinical and genetic data from over 8,500 adults with psychiatric disorders, to assess whether schizophrenia polygenic risk […]

Guidelines for reporting polygenic risk score

Researchers from NIH have developed a 22-item framework, published in Nature, that has identified the minimal polygenic risk score-related information […]

Improving polygenic risk scores

Existing genome-wide association studies have been predominantly conducted in individuals of European descent. In turn, this has limited the transferability […]

How to: perform polygenic risk score analysis

A recent article published in Nature Protocols highlights key issues related to polygenic risk score analyses and provides a starting […]

Night owls may be protected from health risks associated with shift work

Certain individuals may be genetically predisposed to being a night owl, according to a recent study published in the journal […]

Japanese Study Identifies 35 Genetic Risk Factors for Atrial Fibrillation

In a new study published in Nature, researchers have identified 35 genetic susceptibility loci for atrial fibrillation (AF) in a […]

A Spotlight On: Risk Genes for Psychiatric Disorders – Derek Morris

Derek Morris, Senior Lecturer in Biomedical Science at the University of Galway, joins us to discuss the genetics behind psychiatric […]