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Search results for: Polygenic Risk Scores

Polygenic background modifies penetrance of monogenic variants

Researchers have found that polygenic background can modify penetrance of disease in tier 1 genomic conditions. Monogenic variants Monogenic variants […]

Genetic risk for Alzheimer’s progression differs with sex

It is well documented that the genetic risk for Alzheimer’s has a sex bias. Sex bias in Alzheimer’s Carrying a […]

The Genetics Of Alzheimer’s: Uncovering new Mechanisms and Drug Targets

An understanding of the environmental and genetic risk of Alzheimer’s Disease is vital for the production of more effective therapies. […]

Genome UK: The future of healthcare

Genome UK The UK has launched its new National Genomic Healthcare Strategy, with the goal of cementing its status as […]

African genomics needed for genetic medicine

As part of the 20th anniversary of Nature Reviews Genetics, Professor Ambroise Wonkam from the University of Cape Town has […]

Machine learning identifies epigenetic markers of Schizophrenia

We know from twin studies that Schizophrenia carries a 80% heritability risk, but haven’t yet managed to deduce exact genetic […]

Interview with Rory Collins, Principal Investigator and Chief Executive of UK Biobank

Rory Collins, Principal Investigator and Chief Executive of UK Biobank leads this landmark project. We talk to him about some of the research outcomes from UK Biobank, and why he’s excited to be speaking at the Festival of Genomics this January.