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Mitochondrial DNA genotype-phenotype interactions

A recent study has found that genetic variants in mitochondrial DNA could increase the risk of developing several common diseases, […]

Phenotype prediction accuracy limited by negative selection

Using population genetic models, researchers show that negative selection on complex traits limits phenotype prediction accuracy between populations. Phenotype prediction […]

Mitochondrial stress: a phenotype of spaceflight

Spaceflight is known to impact human physiology, but the distinct molecular aetiologies are unknown. In a recent study, published in […]

Pheno-RNA: a method to associate genes with phenotypes

In a recent article, published in PNAS, researchers have described a new method – Pheno-RNA – to identify candidate genes […]

Human brain-derived proteome data helps elucidate a genetic causal pathway for neurological phenotypes

A team of researchers have analysed human proteome data from brain tissue to study whether targeted proteins predictively mediated the […]

Social behaviours influenced by genetic and environmental factors

A team of researchers from the University of Utah have discovered that inhibition of the enzyme topoisomerase IIα (Top2a) during […]

Cancer clone maps provide direction on breast cancer metastasis

There are around 55,900 new breast cancer cases in the UK every year – more than 150 cases every day. […]

Leukaemias ‘re-programme’ themselves using epigenetic regulators

Some leukaemias are able to alter the proteins they express on the cell surface in order to evade cancer treatment. […]

Searching in the dark: The role of epigenetics in cancer development

New research, led by scientists at The Institute of Cancer Research, the Human Technopole in Milan, and Queen Mary University […]

A Spotlight On: Risk Genes for Psychiatric Disorders – Derek Morris

Derek Morris, Senior Lecturer in Biomedical Science at the University of Galway, joins us to discuss the genetics behind psychiatric […]