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Mitochondrial DNA genotype-phenotype interactions

A recent study has found that genetic variants in mitochondrial DNA could increase the risk of developing several common diseases, […]

Phenotype prediction accuracy limited by negative selection

Using population genetic models, researchers show that negative selection on complex traits limits phenotype prediction accuracy between populations. Phenotype prediction […]

Mitochondrial stress: a phenotype of spaceflight

Spaceflight is known to impact human physiology, but the distinct molecular aetiologies are unknown. In a recent study, published in […]

Pheno-RNA: a method to associate genes with phenotypes

In a recent article, published in PNAS, researchers have described a new method – Pheno-RNA – to identify candidate genes […]

Human brain-derived proteome data helps elucidate a genetic causal pathway for neurological phenotypes

A team of researchers have analysed human proteome data from brain tissue to study whether targeted proteins predictively mediated the […]

Week in Brief: Week Ending 5th July

Happy Monday everyone, and welcome back to Week in Brief, your stop for all the latest genomics news! Blood disorders […]

The Rise (And Fall?) of Genomics: The Omics Revolution

As technology advances, we’re used to hearing about the latest in a seemingly never-ending list of ‘omics’. With each one […]

The State Of: Multi-Omics

This feature was written by Taylor Fulton-Ward. The advent of multi-omics, or the combination of different omics for analysis, has […]

The Big Challenge… With Jill Maron

With the ever-increasing potential of new technology and the exponential growth of the life sciences field, researchers are always running […]

Proteogenomics in Drug Discovery: Appreciating the Big Picture

The use of genomics in drug discovery has been heralded as a revolutionary tool. With most drugs ultimately failing at […]