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Transplanted Brain Organoids Functionally Integrate with Adult Rat Brains

In a recent study published in Cell Stem Cell, researchers have successfully transplanted human brain organoids into the brains of […]

Evaluation of Colorectal Cancer Organoids by Single-Cell RNA-Seq

Written by Charlotte Harrison, Science Writer Organoids, which are cell-derived 3D culture system, are emerging as a powerful model for […]

Lab-grown brain organoids develop rudimentary eyes

A new study, published in Cell Stem Cell, has grown brain organoids in the lab that developed basic eye structures, […]

Pan-cancer tumour organoids pave the way towards precision medicine

Researchers have developed a platform of pan-cancer tumour organoids and a neural-network-based drug assay, that has the potential to advance […]

New Study Comprehensively Maps Placental Development in Unprecedented Detail

In a recent study published in Nature, researchers have mapped placental development from start to finish. They used single-cell, spatial-omics, […]

Base editing successfully corrects immune deficiency mutation

Researchers have used base editing to correct the mutation that causes a rare immune disorder. A one-off gene therapy could […]

New genes implicated in COVID-19 infection

A new study, published this week in Nature Cell Biology, describes the role of the CIART gene in COVID-19 infection. […]

Advanced Research Models ONLINE

We frequently read articles about how diseases have been reversed, halted and cured in mice, yet effective treatments for humans […]

Comprehensive sequencing of the small intestine reveals “collateral damage” by APOBEC1 enzyme may lead to cancer

Researchers at the Wellcome Sanger Institute have found that the enzyme APOBEC1 may cause the mutations SBS2 and SBS13 – […]

Targeting Pyroptosis – A Promising Strategy for Overcoming Chemotherapy Resistance?

A new study published in Science suggests that targeting pyroptosis, a type of programmed cell death, may be a promising […]