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How-to: Infer Gene Regulatory Networks from Omics Data

This feature was put together using content from Chapter 5 of the Multi-omics Playbook, released in February 2024. For an […]

How-to: Profile the epigenome

The epigenome regulates the expression of genes without altering their underlying DNA sequence. Comprising a dynamic landscape of chemical modifications […]

Epigenetics and Ancestry: How Our History Shapes Who We Are

The idea that the experiences of our ancestors shape who we are today is not a novel one. In fact, […]

Researchers Identify “Rules” for Effective CRISPR Activation

Researchers have conducted a study, published in Molecular Cell, to investigate what features influence how well CRISPR activation works for […]

New blood test for prostate cancer shows 94% accuracy

When used in combination with the standard prostate-specific antigen test for prostate cancer (PCa), a new epigenetic assay can improve […]

Researchers Investigate the Epigenetic Regulation of NRG1 in Breast Cancer Under Hyperglycaemia

In a new study published in Nature, researchers investigated the molecular mechanisms behind the epigenetic regulation of the NRG1 enhancer […]

New Study profiles the Epigenome of Renal Cell Carcinomas

A new study published in Nature has shed light on the epigenome of renal cell carcinomas (RCCs), the most common […]

An overview of -omics technologies in multi-omics

A multi-omics approach involves the combining of different “omics”: genomics, epigenomics, transcriptomics, and proteomics. The simultaneous study of each “omic” […]

A guide to multi-omics

Multi-omics is the combining of different “omics” – the genome, epigenome, transcriptome and proteome. Studying each layer in isolation can […]

A Spotlight On: Spatial Transcriptomics – Jeffrey Moffitt, Assistant Professor, Harvard Medical School

Jeffrey Moffitt is an Assistant Professor at Boston Children’s Hospital and Harvard Medical School. His lab uses state-of-the-art spatially resolved […]