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GTEx project sheds light on gene expression

Scientists from the Genotype-Tissue Expression (GTEx) project have completed a range of studies documenting how small changes in the DNA […]

Differential gene expression analysis reveals new genetic variants implicated in oral cancer

A study published in Scientific Reports, has identified six significant oral cancer associated genes through differential analysis. Oral cancer Oral […]

Monocyte gene expression provides insight into depression

A recent paper, published in Translational Psychiatry, uses monocyte gene expression to gain insight into childhood trauma, suicide risk and […]

Controlling gene expression with computer-inspired protein gates

Scientists have designed tools to regulate protein-protein interactions, akin to the structure of electronics, that are capable of controlling T-cell […]

CRISPR system developed for dose-dependent gene expression

CRISPR is renowned for its precise gene-editing ability, but is gaining ground in alternative applications; namely the control of selected […]

Non-Genetic Mechanisms of Therapeutic Resistance in Cancer

Therapeutic resistance has repeatedly proved itself to be an unconquerable barrier for curative cancer treatment. However, recent investigations have challenged […]

The Genetics Of Alzheimer’s: Uncovering new Mechanisms and Drug Targets

An understanding of the environmental and genetic risk of Alzheimer’s Disease is vital for the production of more effective therapies. […]

Genetic modifiers impact long-term survival in sickle cell anaemia

A study published in Clinical and Translational Medicine, has assessed whole-exome sequencing data from sickle cell anaemia patients to identify […]

Researchers identify five gene candidates linked to insomnia

A team of researchers from China have performed an integrative genomic analysis and identified five genes associated with insomnia. Insomnia […]

Variants in ACE2 and TMPRSS2 may explain genetic susceptibility towards COVID-19

The current COVID-19 pandemic has revealed that increased age and the presence of co-existing health conditions, such as cancer, cardiovascular, […]