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GTEx project sheds light on gene expression

Scientists from the Genotype-Tissue Expression (GTEx) project have completed a range of studies documenting how small changes in the DNA […]

Differential gene expression analysis reveals new genetic variants implicated in oral cancer

A study published in Scientific Reports, has identified six significant oral cancer associated genes through differential analysis. Oral cancer Oral […]

Monocyte gene expression provides insight into depression

A recent paper, published in Translational Psychiatry, uses monocyte gene expression to gain insight into childhood trauma, suicide risk and […]

Controlling gene expression with computer-inspired protein gates

Scientists have designed tools to regulate protein-protein interactions, akin to the structure of electronics, that are capable of controlling T-cell […]

CRISPR system developed for dose-dependent gene expression

CRISPR is renowned for its precise gene-editing ability, but is gaining ground in alternative applications; namely the control of selected […]

Researchers identify role of gene in placental development

A recent study has shown that the gene GPR126 plays an essential role in the development of the placenta during […]

Genetic signature of treatment resistance in breast cancer identified

Researchers have discovered a genetic signature that can identify drivers of poor outcomes in advanced oestrogen-receptor positive (ER+) breast cancer. […]

Generating a proteo-genomic map of human health

Researchers at Medical Research Council Epidemiology have carried out a genome-proteome-wide association study that targeted 4,775 distinct proteins, enabling them […]

Interpreting genetic variants in type 2 diabetes

Numerous genetic variants in the human genome have been linked to type 2 diabetes. However, as most of these variants […]

Can we be genetically predisposed to psychiatric disease and addiction?

A recent study, published in NeuroResource, has used single-nucleus transcriptome analysis to identify cell-type-specific molecular signatures in the brain that […]