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‘Druggable’ pockets in SARS-CoV-2 protein offer new therapeutic targets

The COVID-19 pandemic was controlled due to the rapid development of new vaccines and anti-viral drugs. However, the emergence of […]

Why do some prostate cancer drugs fail?

Written by Lauren Robertson, Science Writer New research suggests some prostate cancer drugs may change how certain prostate tumours function, […]

Local delivery of anti-CTLA-4 cancer immunotherapy drug is safer than systemic delivery

Results from a clinical trial suggest that local delivery of anti-CTLA-4 immunotherapy drug is safer than systematic delivery. The study, […]

Rectal cancers disappear in a dostarlimab experimental drug trial

A new drug trial has eliminated 100% of rectal tumours in patients after 6 months. Published in the New England […]

Genome-wide CRISPR and tumour suppressor genes could open new pathways for discovering anticancer drugs

Researchers at the University of Texas have performed genome-wide CRISPR screens to uncover vulnerabilities critical for discovering anticancer drugs. The […]

Anti-PD-1: The immunotherapy drug that reverses obesity-associated breast cancer

Researchers have discovered that treatment of breast cancer with a checkpoint inhibitor drug, called anti-PD-1, significantly reduces obesity-associated tumour burden. […]

The Genetics Of Alzheimer’s: Uncovering new Mechanisms and Drug Targets

An understanding of the environmental and genetic risk of Alzheimer’s Disease is vital for the production of more effective therapies. […]

New class of precision oncology drug strips cancer of its DNA defences

Damage to the DNA in cells is the root cause of cancer, but it is also a weakness of the […]

FDA releases list of evidence-based pharmacogenetic variants

Pharmacogenetics (PGx) is the study of how an individual’s genetic makeup affects their drug response and metabolism. An understanding of PGx could help clinicians make prescribing decisions and has the potential to be implemented in routine care worldwide. PGx has understandably been gaining traction and support, with pharmacogenomic elements being implemented into many international Genomic studies.

Proteomics ONLINE

Proteomics is set to play a huge role in the post-genomic era – especially in the context of drug discovery. […]