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DNA methylation associated with obesity and diabetes

A new study, published in Nature Communications, has combined epigenome-wide association and integrative genomics to explore adipocyte DNA methylation in […]

Gene expression changes contribute to Type 2 diabetes disease pathology

A study, recently published in the Journal of Clinical Investigation, has revealed nearly 400 genes that are expressed differentially in […]

Grizzly bear insulin control mechanism could aid diabetes treatment

Written by Lauren Robertson, Science Writer. Proteomics and transcriptomics analysis has uncovered the genetic key to the brown bear’s ability […]

Interpreting genetic variants in type 2 diabetes

Numerous genetic variants in the human genome have been linked to type 2 diabetes. However, as most of these variants […]

Reversing diabetes with a selective microRNA inhibitor

Researchers have designed a structure-specific microRNA inhibitor that selectively represses a microRNA family member, which may in turn reverse the […]

A substantial genetic contributor to loss of Y chromosome and type 2 diabetes

Researchers have identified loss-of-function GIGYF1 variants that contribute more to the risk of loss of Y chromosome and type 2 […]

HLA-DR4: The human antigen with subtypes that are strongly linked to type 1 diabetes

Researchers have identified three amino acid residues that are responsible for the variable association of HLA-DR4 subtypes with type 1 […]

A cellular culprit for type 1 diabetes

By harnessing various genetic tools, researchers have identified a predictive causal role for specific cell types in type 1 diabetes. […]

Overlapping genetic association in type I and type II diabetes

Due to the potential shared aetiology between type I and type II diabetes, researchers recently aimed to identify any genetic […]

COVID-19 linked to type 1 diabetes in children

A recent study, published in Diabetes Care, has reported a potential link between COVID-19 and the development of type 1 […]