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Transcriptome and circular DNA sequencing in single cancer cells

A new single-cell sequencing method has been published in Nature Genetics. Single-cell extrachromosomal circular DNA and transcriptome sequencing (scEC&T-seq) can […]

New DNA sequencing technique sets world record

A team from Stanford Medicine has set a Guinness World Record for the fastest time to sequence a whole genome. […]

Genetics Unzipped podcast: A brief history of DNA sequencing

In the latest episode of Genetics Unzipped, presenter Dr Kat Arney takes a look at how we learned to read […]

DNA Sequencing: How to Choose the Right Technology

Introduction It has been over 30 years since the first generation of DNA sequencing technology was developed in 1977. Since […]

The evolution of DNA sequencing technologies

The order of nucleotides within a sequence of DNA is important. It underpins subsequent protein function and, in cases of […]

Sequencing of DNA in the bone marrow can predict leukaemia relapse

DNA sequencing-based detection of residual disease has been found to accurately predict which acute lymphoblastic leukaemia patients will eventually relapse. […]

New Commercial Developments in Single-cell Sequencing

This feature on single-cell sequencing technology is adapted from parts of Chapters 1 & 2 of the 2023 Spatial and […]

Paleogenomics and ancient DNA: How can the past inform the future?

When it comes to the use of genomics in modern healthcare, the vast majority of studies focus on individuals alive […]

Genomic sequencing fine-tunes prostate cancer diagnosis

A study from Nature Medicine has significantly refined the use of prostate-specific antigen (PSA) screening for prostate cancer using an […]

DNA methylation associated with obesity and diabetes

A new study, published in Nature Communications, has combined epigenome-wide association and integrative genomics to explore adipocyte DNA methylation in […]