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Differential DNA methylation contributes to risk of multiple sclerosis

A recent study has discovered differentially methylated genomic regions harbouring 4 loci associated with risk of multiple sclerosis. Multiple sclerosis […]

The functional importance of unusual DNA structures called G4s has been revealed

For the first time, researchers have found that G-quadruplex structures (G4s) in DNA could be added to the list of […]

Polθ: Human Cells can write RNA sequences into DNA

Researchers have discovered that mammalian cells can convert RNA sequences back into DNA using Polθ, which challenges long-believed notions surrounding polymerases. Polymerases […]

The effects of DNA methylation on 3D structure

Researchers have explored how methylation patterns have a protein-independent regulatory role that increases the stiffness of DNA, which ultimately impacts […]

Mitochondrial DNA genotype-phenotype interactions

A recent study has found that genetic variants in mitochondrial DNA could increase the risk of developing several common diseases, […]

Cancer cells take advantage of DNA’s 3D structure

Researchers have explored how cancer cells re-organise the 3D structure of their DNA to enhance oncogene activity. Cancer cells In […]

A new way to produce synthetic DNA

Researchers from Aarhus University have developed a new and efficient way to streamline the process of synthetic DNA production. Synthetic […]

DNA analysis identifies sailor from 1845

Researchers have identified the skeletal remains of a member of the 1845 Franklin expedition by DNA analysis. The 1845 Franklin […]

Dozens of phages use Z-DNA base

Researchers have looked in detail at how phages use Z-DNA to evade the attack of host restriction enzymes. DNA modifications […]

Evaluation of ctDNA assays for precision oncology

An international team has reported findings from an independent assessment of five commercially available ctDNA assays as a method to […]