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CPT1A upregulation promotes colon cancer

A paper published in Cell Death and Disease, has identified that CPT1A upregulation is important for the tumour promoting effects […]

Let’s talk about colon cancer

The recent passing of actor and role model, Chadwick Boseman, from colon cancer has shocked the nation. This shock seems […]

Non-Genetic Mechanisms of Therapeutic Resistance in Cancer

Therapeutic resistance has repeatedly proved itself to be an unconquerable barrier for curative cancer treatment. However, recent investigations have challenged […]

EGFR: Marker for prostate cancer dissemination

Researchers have reported EGFR overexpression as a stable marker for prostate cancer dissemination to rigid organs, preferentially bones. Prostate cancer […]

Methylmalonic acid represents a link between ageing and cancer

A study published in Nature has explored the role of age-induced accumulation of methylmalonic acid in cancer progression. Disease of […]

Representative sampling method improves the genetic testing for cancer treatment

A wholistic tumour sampling method developed by researchers from The Francis Crick Institute, Roche, and The Royal Marsden NHS Foundation […]

Polygenic background modifies penetrance of monogenic variants

Researchers have found that polygenic background can modify penetrance of disease in tier 1 genomic conditions. Monogenic variants Monogenic variants […]

HIV: origins, treatment and the continued stigma

The first person to be cured of HIV, Timothy Ray Brown, died last week from a recurrence of leukaemia. His […]

Oncogenic mutational processes differ between sexes

A recent pan-cancer analysis has uncovered sex differences in oncogenic mutational processes.  Cancer sex disparities Disparities between sexes have been […]