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Chromothripsis: A driver of gene amplification in cancer

Researchers have used whole-genome sequencing (WGS) to show that chromothripsis is a major driver of circular extrachromosomal DNA amplification. Gene […]

Key cross-species genes offer insight into human bladder cancer development

Muscle invasive bladder cancer (MIBC) is an aggressive form of human bladder cancer. Little is currently known about the genetic […]