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A key role for the histone chaperone CAF-1 in sustaining cell fate

Written by Charlotte Harrison, Science Writer Cell fate — whether a cell self-renews or differentiates — is driven by dynamic […]

Fluctuating methylation clocks can trace cell fates

Researchers have shown that fluctuating DNA methylation sites can be used as ‘clocks’ to trace the lineage of a cell. […]

The State Of: The Human Cell Atlas Initiative

Announced in 2016, the Human Cell Atlas initiative aims to characterise all cell types in the human body. Led by […]

Key transcription factor for stem cell differentiation linked to cancer

Stem cells are unspecialised cells, defined by their capacity for self-renewal and ability to differentiate into a variety of somatic […]

Revealing the genetic diversity of drug-resistant cancer cells

In a recent  Nature paper, researchers have developed a new methodology to track the fates of cancer cells after therapy. […]

A Spotlight On: Single Cell Proteomics – Nikolai Slavov, Professor, Northeastern University

Nikolai Slavov is an Allen Distinguished Investigator and Professor at Northeastern University. His work focuses on single cell proteomics and […]

Cell atlas of the human uterus

The most comprehensive cell atlas to date of the human uterus has uncovered two new epithelial cell states that can […]

Researchers find 300 proteins that regulate cell division

Researchers from Sweden have published a new molecular mapping of proteins that regulate the cell division process – identifying 300 […]

Eleven challenges in single-cell data science

Introduction: Single-cell sequencing technology has been advanced by the falling sequencing costs, a boom in microfluidics and combinatorial indexing strategies. […]

How-to: Infer Gene Regulatory Networks from Omics Data

This feature was put together using content from Chapter 5 of the Multi-omics Playbook, released in February 2024. For an […]