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Genome-wide Screens Identify Genes that Dampen Immunosurveillance in Cancer

Tumours often avoid detection by CD8+ T cells through disrupting peptide presentation by major histocompatibility complex class I (MHC-I). However, […]

Native American Ancestry Linked To Increased EGFR Mutations In Latin American Patients With Lung Cancer

A recent study, published by the American Association for Cancer Research has discovered that among patients with lung cancer from […]

CAR-T cell therapy shows promise against rare childhood cancer

A novel CAR-T cell therapy, developed by researchers at UCL and designed to target cancerous tumours, has shown early promising […]

HPV integration signatures in cervical cancer

A team of researchers have analysed the association between different human papilloma virus (HPV) integration signatures, clinical parameters and outcomes […]

CRISPR system destroys cancer cells

Researchers have utilised lipid nanoparticles to deliver CRISPR technology and found that this technology could destroy cancer cells within an […]

Lung microbiome implicated in lung cancer pathogenesis and prognosis

A recent paper, published in Cancer Discovery, has found that enrichment of the lungs with oral commensal microbes was associated […]

Distinct genetic alterations found in African American men with prostate cancer

Researchers have found that prostate cancer tumours from African American men harboured higher frequencies of distinct genetic alterations that may […]

PRMT5: synthetic lethality target in pancreatic cancer cells

A team of researchers have used targeted CRISPR screening and have identified PRMT5 as a synthetic lethality combinatorial target with […]

Breast Cancer Awareness Month: On Fridays we wear pink

October is Breast Cancer Awareness month and on Friday (23rd October) charities are encouraging individuals to wear pink to raise […]

Non-Genetic Mechanisms of Therapeutic Resistance in Cancer

Therapeutic resistance has repeatedly proved itself to be an unconquerable barrier for curative cancer treatment. However, recent investigations have challenged […]