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RNA Editing: The New CRISPR?

RNA therapeutics have gained traction over the last four years, not least because of the significant global effort to create […]

Back to Basics – CRISPR

Recent news has been filled with stories of CRISPR gene editing reaching the clinic, but the technique has been at […]

TIGER: a tool to predict CRISPR–Cas13 off-target activity

‘TIGER: a tool to predict CRISPR–Cas13 off-target activity‘ – Written by Charlotte Harrison, Science Writer. CRISPR technology that targets RNA […]

CRISPR editing in the lung

Written by Charlotte Harrison, Science Writer Delivering gene therapies to the lung is challenging because of its specialized cell types […]

Researchers Identify “Rules” for Effective CRISPR Activation

Researchers have conducted a study, published in Molecular Cell, to investigate what features influence how well CRISPR activation works for […]

CRISPR competitor? Deep-learning model for zinc finger design aids transcription factor reprogramming

A new study, published in Nature, outlines an AI-based approach that could help overcome some of the challenges with zinc […]

A new CRISPR protein may be the key to better viral diagnostics

A team of researchers from the University of Texas at Austin have discovered a new CRISPR-associated (Cas) protein that can […]

CRISPR-based therapy alleviates Huntington’s disease symptoms in mouse models

Researchers have investigated the application of RNA-targeting CRISPR technology in the treatment of Huntington’s disease (HD). The study, published in […]

Virus-derived CRISPR systems may be added to the gene-editing toolbox

The CRISPR-Cas9 system revolutionised genome editing approaches. Recent work on the CRISPR gene editing technology won the 2020 Nobel Prize […]

CRISPR technology alters immune cells to fight cancer

Researchers at the University of California, Los Angeles, have combined the use of CRISPR gene therapy with engineered immune cells […]