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CRISPR screens identify drivers of ageing in the brain

Using high-throughput CRISPR-Cas9 screens, researchers have systematically uncovered gene knockouts that impact ageing in neural stem cells of the brain. […]

Drag-and-drop CRISPR genome integration

Researchers have developed a CRISPR-based approach that enables direct genome integration without generating double-strand breaks. Genome integration Programmable genome insertion […]

Researchers have engineered a new miniature CRISPR-Cas System

CRISPR-Cas systems have revolutionised genomic research, offering precise genome editing. However, there still is clinical demand for a compact and […]

New CRISPR-Cas System is Found to Cut RNA

Researchers at the Delft University of Technology have discovered a new CRISPR-Cas system that is able to cut viral RNA […]

Modified guide RNAs boost CRISPR-Cas13 transcript knockdown

Researchers at New York University and the New York Genome Center have developed chemically modified guide RNAs that enhance CRISPR-Cas13 […]

Envisioning a CRISPR/Cas9-based therapy for retinitis pigmentosa

A proof-of-principle study has shown that template-free CRISPR/Cas9 gene editing can correct mutations that cause X-linked retinitis pigmentosa in mouse […]

The view from space is CRISPR

Astronauts aboard the International Space Station have performed the first successful use of CRISPR-Cas9 genome editing in space. Ionising radiation […]

CRISPR injected into the blood treats genetic disease

For the first time, researchers have injected CRISPR into the blood of people with a genetic disease and shown that […]

Check your CRISPR-Cas9 edits Cautions Crick

CRISPR-Cas9 is currently one of the most significant gene-editing tools. Its discovery won the Nobel Prize for Chemistry last year. […]

Genetics Unzipped podcast: A brief history of CRISPR – how we learned to edit the genome

In the latest episode of Genetics Unzipped, presenter Kat Arney takes a look at the history of gene editing, from […]