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Genetic signature of treatment resistance in breast cancer identified

Researchers have discovered a genetic signature that can identify drivers of poor outcomes in advanced oestrogen-receptor positive (ER+) breast cancer. […]

Anti-PD-1: The immunotherapy drug that reverses obesity-associated breast cancer

Researchers have discovered that treatment of breast cancer with a checkpoint inhibitor drug, called anti-PD-1, significantly reduces obesity-associated tumour burden. […]

Super-enhancers switch on breast cancer genes

Researchers have identified and characterised a set of specific super-enhancers that stimulate the activity of critical breast cancer genes. Breast […]

Triple-negative breast cancers accumulate genetic changes during growth

Using a novel method for single-cell DNA sequencing, researchers have revealed for the first time that triple-negative breast cancers undergo […]

Breast Cancer Awareness Month: On Fridays we wear pink

October is Breast Cancer Awareness month and on Friday (23rd October) charities are encouraging individuals to wear pink to raise […]

MiR-93 as a potential novel target for breast cancer

A new study published in Cell Death and Disease has revealed the role of miR-93 in tumorigenesis and chemosensitivity. Breast […]

Genetic variants linked to male breast cancer found

A recent study published in the Journal of the National Cancer Institute has discovered three genetic variants linked to an […]

Researchers unravel the role of G-quadruplexes in breast cancer

A team of researchers from the University of Cambridge have unravelled the complex landscape of G-quadruplexes and revealed their role […]

Studying cancer through the lens of protein-protein interactions

Researchers at the Cancer Cell Map Initiative have explored hundreds of previously unknown protein-protein interactions suspected to drive cancer. Their […]

The Cancer Gene Directory

BRCA1 gene Name: BReast CAncer gene 1 Type of gene: Tumour suppressor gene responsible for repairing DNA located on chromosome […]