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Base editing extends lifespan of mice with progeria

Researchers have successfully used a base editing technique to extend the lifespan of mice with the genetic variant associated with […]

Base editing outcomes predicted by machine learning model

Single nucleotide variants (SNVs) are implicated in about half of all genetic diseases and so, accurately targeting and editing these […]

Fine tuning base editors to avoid gene-editing errors

Researchers at Rice University have developed a new approach that improves the avoidance of gene-editing errors in base editing strategies. […]

A New Dawn for Mitochondrial Genome Editing

Written by Bethany Hoernfeldt, Science Writer  Researchers have successfully facilitated A-to-G base conversion in mitochondrial DNA, ushering in a new […]

What’s the Best Way to Deliver Prime Editing?

Written by Charlotte Harrison, Science Writer  Prime editing is a new type of genome editing technology. It essentially builds on […]

Should COVID-19 Vaccines be Prioritized Based on Genetics?

Written by Charlotte Harrison, Science Writer  Evidence suggests that a person’s genetic make-up may be at least partly responsible for […]

Improving prime editing by studying DNA repair

A group of researchers has shown that the DNA mismatch repair process plays a critical role in prime editing. Genome […]

First genome editing on blood vessel walls

Researchers have developed a unique nanoparticle to deliver genome editing technology to endothelial cells. This is the first time that […]

Envisioning a CRISPR/Cas9-based therapy for retinitis pigmentosa

A proof-of-principle study has shown that template-free CRISPR/Cas9 gene editing can correct mutations that cause X-linked retinitis pigmentosa in mouse […]

Base editor treats sickle cell disease in mice

A team led by researchers at the Broad Institute and St. Jude Children’s Research Hospital has now demonstrated that a […]