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Base editing successfully corrects immune deficiency mutation

Researchers have used base editing to correct the mutation that causes a rare immune disorder. A one-off gene therapy could […]

Treating inherited deafness with RNA base editing

Using RNA base editing techniques, scientists have successfully reversed a genetic form of hearing loss in a mouse model. The […]

Base editing extends lifespan of mice with progeria

Researchers have successfully used a base editing technique to extend the lifespan of mice with the genetic variant associated with […]

Base editing outcomes predicted by machine learning model

Single nucleotide variants (SNVs) are implicated in about half of all genetic diseases and so, accurately targeting and editing these […]

Base and Prime Genome Editing in Precision Oncology

This feature on prime and base editing is adapted from content provided in the Cancer Genomics 2023 Report. The introduction […]

Fine tuning base editors to avoid gene-editing errors

Researchers at Rice University have developed a new approach that improves the avoidance of gene-editing errors in base editing strategies. […]

Unlocking the future: where is gene editing going next?

As advancements in genetic technologies accelerate at an astonishing pace, the potential for gene editing to transform our world becomes […]

Cell-based study corrects fragile X syndrome

Written by Charlotte Harrison, Science Writer. A new paper published in Cell describes an approach to correct the genetic defect […]

Prime editing successfully corrects sickle cell mutation

Researchers have used prime editing to correct the mutation that causes sickle cell disease in patient-derived stem cells. The study, […]

CRISPR editing in the lung

Written by Charlotte Harrison, Science Writer Delivering gene therapies to the lung is challenging because of its specialized cell types […]