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BTG1 Mutations Play Key Role in Diffuse Large B Cell Lymphomas

A recent study published in Science has uncovered new insights into the mechanisms underlying poor outcomes in Diffuse Large B […]

Largest scRNA spatial atlas of B cells in lung cancer revealed

Written by Lauren Robertson, Science Writer. Researchers from the University of Texas MD Anderson Cancer Center have revealed the largest […]

The abscopal effect and B cells’ surprising role in treating hard to reach tumours

A new study in mice finds that B cells unexpectedly promote the therapeutic shrinking of breast cancer tumours, even when they are not the direct targets of local immunotherapy.  The […]

New Commercial Developments in Single-cell Sequencing

This feature on single-cell sequencing technology is adapted from parts of Chapters 1 & 2 of the upcoming Spatial and […]

Hidden Stem Cells Found in Human Thymus 

A new study published this week in Developmental Cell has identified the presence of stem cells in the human thymus […]

Methods to study cell-cell communication from single-cell sequencing data

This feature on cell-cell communication is adapted from part of Chapter 4 of the upcoming Spatial and Single-cell Playbook, due […]

LSD1 promotes prostate cancer cell reprogramming through TP53 repression

Prostate cancers are generally treatable with positive survival outcomes. However, following common treatments such as androgen receptor inhibitors, some prostate […]

Key transcription factor for stem cell differentiation linked to cancer

Stem cells are unspecialised cells, defined by their capacity for self-renewal and ability to differentiate into a variety of somatic […]

Revealing the genetic diversity of drug-resistant cancer cells

In a recent  Nature paper, researchers have developed a new methodology to track the fates of cancer cells after therapy. […]

B-cell responses belittled in mitochondrial disorders

‘B-cell responses belittled in mitochondrial disorders‘ – Written by Charlotte Harrison, Science Writer  Mitochondrial diseases are a group of genetic […]